Inter-subject variability and normal limits of the SITA standard, SITA fast, and the Humphrey full threshold computerized perimetry strategies, SITA STATPAC

Inter-subject variability and normal limits of the SITA standard, SITA fast, and the Humphrey full threshold computerized perimetry strategies, SITA STATPAC
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DOI:
10.1034/j.1600-0420.1999.770201.x
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发表时间:
1999-04-01
期刊:
ACTA OPHTHALMOLOGICA SCANDINAVICA
影响因子:
--
通讯作者:
Heijl, A
Heijl, A
中科院分区:
其他
文献类型:
--
作者:
Bengtsson, B;Heijl, A

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目的:建立和评估新 SITA 策略的受试者间变异性和正常阈值限值,并将其与传统 Humphrey 全阈值算法获得的结果进行比较。方法:从 10 个中心收集 330 名正常受试者的 330 只眼睛的数据,以便建立新 SITA 策略的正常性限值,从而使 SITA 视野接受计算机辅助视野分析成为可能。第二,使用 SITA Standard、SITA Fast 和 Full Threshold 算法进行视野测试。结果:与 Full Threshold 相比,SITA Standard 的受试者间方差小 31%,SITA Fast 的受试者间方差小 41% (p < 0.0001)。与全阈值 (p < 0.0001) 相比,两种 SITA 算法的随年龄变化的差异光灵敏度下降幅度也明显较小,分别为 23% 和 25%。与全阈值 (28.3 dB) 相比,SITA 标准 (29.5 dB) 和 SITA Fast (29.9 dB) 的平均灵敏度稍高 (p < 0.0001)。 SITA 在不同显着性水平下将正常限值收紧在 9% 至 29% 之间。结论:与全阈值视野相比,正常视野眼睛的 SITA 测试结果从中心到中周边平均会更均匀。它们在灰度表示中也会显得稍浅,由于受试者间差异较小,SITA 视野中需要较浅的凹陷才能具有统计和临床意义。
Purpose: To establish and evaluate inter-subject variability and normal threshold limits for the new SITA strategies and to compare them with those obtained with the traditional Humphrey Full Threshold algorithm.Methods: Data from 330 eyes of 330 normal subjects were collected at 10 centres in order to establish limits of normality for the new SITA strategies and thus, to make it possible to subject SITA fields to computer-assisted visual field analysis. Two, visual field tests were obtained with each of the SITA Standard, SITA Fast, and the Full Threshold algorithms.Results: Inter-subject variance was 31% smaller with SITA Standard and 41% smaller with SITA Fast than with Full Threshold (p < 0.0001). Age-dependent decrease of differential light sensitivity was also significantly smaller with both SITA algorithms than with Full Threshold (p < 0.0001), 23% and 25% respectively, Mean sensitivity was somewhat higher with both SITA Standard (29.5 dB) and SITA Fast (29.9 dB) as compared to Full Threshold (28.3 dB) (p < 0.0001). Normal limits were tightened between 9 to 29% at different significance levels with SITA,Conclusion: SITA test results from eyes with normal visual fields will on average be more even from centre to mid-periphery as compared with Full Threshold fields They will also appear slightly lighter in grey-scale representations, Because of smaller inter-subject variance, shallower depressions are needed in SITA fields for statistical and clinical significance.