Adolescent life events as predictors of adult depression

Adolescent life events as predictors of adult depression
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DOI:
10.1016/s0165-0327(00)00331-1
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发表时间:
2002-02-01
影响因子:
6.6
通讯作者:
Brook, JS
Brook, JS
中科院分区:
医学2区
文献类型:
--
作者:
Pine, DS;Cohen, P;Brook, JS

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背景:在成年人中,生活事件可以预测未来重度抑郁症以及一系列焦虑症的发作。虽然研究已经开始在青少年中研究这个问题,但很少有研究依赖前瞻性流行病学设计来记录青少年生活事件与成人重度抑郁症之间的关系。方法:从流行病学角度抽取的 776 名生活在纽约州北部的年轻人样本,于 1986 年接受了基于 DSM 的精神病学评估和生活事件评估。1992 年再次进行了精神病理学评估。当前的研究检验了 1986 年的生活事件与 1992 年的抑郁和焦虑之间的预测关系,并控制了 1986 年的抑郁/焦虑。结果:青少年生活事件预测风险增加用于成年期重度抑郁症的诊断。当连续分析时,发现与重度抑郁症的症状以及广泛性焦虑症的症状存在关联。然而,这种与广泛性焦虑症的关联仅限于女性。结论:青春期的生活事件可以预测成年早期患重度抑郁症的风险。 (C) 2002 Elsevier Science B.V. 保留所有权利。
Background: Among adults, life events predict future episodes of major depression as well as a range of anxiety disorders. While studies have begun to examine this issue in adolescents, few studies rely upon prospective epidemiological designs to document relationships between adolescent life events and adult major depression. Method: An epidemiologically-selected sample of 776 young people living in Upstate New York received DSM-based psychiatric assessments and an assessment of life events in 1986. Psychopathology was again assessed in 1992. The current study examined the predictive relationship between life events in 1986 and depression as well as anxiety in 1992, controlling for depression/anxiety in 1986. Results: Adolescent life events predicted an increased risk for major depression diagnosis in adulthood. When analyzed continuously, an association emerged with symptoms of major depression as well as with symptoms of generalized anxiety disorder. However, this association with generalized anxiety disorder was limited to females. Conclusions: Life events in adolescence predict risk for major depression during early adulthood. (C) 2002 Elsevier Science B.V. All rights reserved.