Synaptic plasticity in the spinal dorsal horn
Synaptic plasticity in the spinal dorsal horn
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DOI：
10.1016/j.neures.2009.03.004
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发表时间：
2009-06-01
影响因子：
2.9
通讯作者：
Murase, Kazuyuki
中科院分区：
文献类型：
--
作者：
Ikeda, Hiroshi;Kiritoshi, Takaki;Murase, Kazuyuki
脊髓背角突触的长时程增强（LTP）被认为是痛觉敏感性异常的细胞机制。本文综述了近年来膜片钳技术和电压敏感染料光学成像技术对脊髓投射神经元LTP的研究进展以及脊髓背角LTP的突触前机制。(C)2009年爱思唯尔爱尔兰有限公司和日本神经科学学会。All rights reserved.
Long-term potentiation (LTP) at synapses in the spinal dorsal horn is thought to be a cellular mechanism for abnormal pain sensitivity. In this article, we review LTP in spinal projection neurons and presynaptic mechanisms of LTP in the spinal dorsal horn revealed by patch-clamp recording and optical imaging with voltage-sensitive dye. (C) 2009 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.