A simple risk index for rapid initial triage of patients with ST-elevation myocardial infarction: an InTIME II substudy

A simple risk index for rapid initial triage of patients with ST-elevation myocardial infarction: an InTIME II substudy
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DOI:
10.1016/s0140-6736(01)06649-1
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发表时间:
2001-11-10
期刊:
影响因子:
168.9
通讯作者:
Braunwald, E
Braunwald, E
中科院分区:
医学1区
文献类型:
--
作者:
Morrow, DA;Antman, EM;Braunwald, E

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背景快速有效的分诊是ST段抬高型心肌梗死(STEMI)患者急诊心脏护理不可或缺的一部分。预测STEMI死亡率的现有模型包括多达45个变量,但一直显示高龄、心率增加和血压降低是最强的预测因子之一。方法根据InTIME II试验中观察到的13253例STEMI患者的风险关系,我们开发并评估了一个简单的风险指数,使用年龄、心率、和收缩压(SBP)预测30天内死亡率:(心率X [年龄/10](2))/SBP。结果风险指数是死亡风险的一个强(c统计=0.78)和独立的预测因子(p
Background Rapid, effective triage is integral to emergency cardiac care of patients with ST-elevation myocardial infarction (STEMI). Available models for predicting mortality in STEMI include up to 45 variables, but have consistently shown advanced age, Increased heart rate, and decreased blood pressure to be among the strongest predictors.Methods On the basis of observed risk relations among 13 253 patients with STEMI from the InTIME II trial, we developed and assessed a simple risk index using age, heart rate, and systolic blood pressure (SBP) for predicting mortality over 30 days: (heart rate X [age/10](2))/SBP.Findings The risk index was a strong (c statistic=0.78) and independent predictor of mortality risk (p