Effects of Addition of Strontium-Containing Bioactive Glass to 4-META/MMA-TBB-Based Resin on Remineralization of Etched Enamel
Effects of Addition of Strontium-Containing Bioactive Glass to 4-META/MMA-TBB-Based Resin on Remineralization of Etched Enamel
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DOI：
10.1166/jbt.2018.1772
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发表时间：
2018-04
影响因子：
0.1
通讯作者：
M. Iijima;Kyotaro Kawaguchi;M. Kawaguchi;Naohiko Kawamura;I. Mizoguchi
中科院分区：
文献类型：
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作者：
M. Iijima;Kyotaro Kawaguchi;M. Kawaguchi;Naohiko Kawamura;I. Mizoguchi
研究了在4-META/MMA-TBB(4-甲基丙烯酰氧乙基偏苯三酸酐/甲基丙烯酸甲酯-三正丁基硼烷)树脂中添加含锶生物活性玻璃对酸蚀牙釉质再矿化的影响。用含锶生物活性玻璃(SrBG)的4-META/MMA-TBB树脂盘，在人工唾液中浸泡3个月，用磷酸酸蚀釉质块。在酸蚀前后和浸泡过程中对釉质表面进行纳米压痕测试。对普通盘、含氟树脂盘和常规生物活性玻璃含树脂盘进行了比较。浸泡后，用扫描电子显微镜观察釉质表面，用微型X射线光电子能谱测定牙釉质表面的元素深度分布。与普通树脂盘和含氟树脂盘相比，酸蚀后牙釉质固定在含SrBG树脂盘上1周后的力学性能明显恢复。尽管附着在普通树脂盘上的釉质试件表面非常多孔，但是附着在含氟、BG或SrBG树脂盘上的浸渍试件在浸泡后表面粗糙度较小。元素分析证实，在人工唾液中浸泡含锶树脂时，酸蚀釉质表面由羟基磷灰石转化为锶磷灰石。因此，含SrBG的树脂粘结剂可以加速酸蚀牙釉质的再矿化。
We investigated the effects of the addition of strontium-containing bioactive glass to a 4-META/MMA-TBB (4-methacryloxyethyl trimellitic anhydride/methyl methacrylate-tri-n-butyl borane)-based resin on the remineralization of etched enamel. Human enamel blocks were etched with phosphoric acid immersed in artificial saliva for 3 months with 4-META/MMA-TBB-based resin disks containing Sr-containing bioactive glass (SrBG). Nanoindentation testing of the enamel surfaces was conducted before and after etching and during the immersion. Plain disk, fluoride-containing resin disk, and conventional bioactive glass-containing resin disks were compared. After immersion, enamel surfaces were observed by scanning electron microscopy and the elemental depth profiles were determined by microscale X-ray photoelectron spectroscopy. The mechanical properties of the etched enamel specimens fixed to SrBG-containing resin disks recovered significantly compared to those attached to the plain and fluoride-containing resin disks after 1 week of immersion. Although the immersed enamel specimens attached to the plain resin disks had very porous surfaces, the immersed specimens attached to the fluoride-, BG-, or SrBG-containing resin disks showed less surface roughness after immersion. Elemental analysis confirmed that the etched enamel surface was converted from hydroxyapatite to strontium apatite during immersion with the Sr-containing resin in artificial saliva. Thus, SrBG-containing resin adhesives can accelerate the remineralization of etched enamel.