The impact of iron deficiency and anaemia on exercise capacity and outcomes in patients with chronic heart failure. Results from the Studies Investigating Co-morbidities Aggravating Heart Failure
The impact of iron deficiency and anaemia on exercise capacity and outcomes in patients with chronic heart failure. Results from the Studies Investigating Co-morbidities Aggravating Heart Failure
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DOI：
10.1016/j.ijcard.2015.11.178
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发表时间：
2016-02-15
影响因子：
3.5
通讯作者：
von Haehling, Stephan
中科院分区：
文献类型：
--
作者：
Ebner, Nicole;Jankowska, Ewa A.;von Haehling, Stephan
贫血和缺铁（ID）是慢性心力衰竭（HF）患者的重要合并症，两者都可能导致运动能力下降。方法：纳入331例稳定型慢性HF门诊患者（平均年龄64 +/- 11岁，女性17%，左室射血分数[LVEF] 35 +/- 13%，体重指数[BMI] 28.5 +/- 5.2 kg/m(2)，纽约心脏协会[NYHA]分级2.2 +/- 0.7，慢性肾病35%，肾小球滤过率61.7 +/- 20.1mL/min）。贫血是根据世界卫生组织的标准定义的（男性血红蛋白[Hb] < 13 g/dL，女性< 12 g/dL）。ID定义为血清铁蛋白
Anaemia and iron deficiency (ID) are important co-morbidities in patients with chronic heart failure (HF) and both may lead to reduced exercise capacity.Methods: We enrolled 331 out-patients with stable chronic HF (mean age: 64 +/- 11 years, 17% female, left ventricular ejection fraction [LVEF] 35 +/- 13%, bodymass index [BMI] 28.5 +/- 5.2 kg/m(2), New York Heart Association [NYHA] class 2.2 +/- 0.7, chronic kidney disease 35%, glomerular filtration rate 61.7 +/- 20.1mL/min). Anaemia was defined according to World Health Organization criteria (haemoglobin [Hb] < 13 g/dL in men, < 12 g/dL in women). ID was defined as serum ferritin