HIV epidemiology in Greece

HIV epidemiology in Greece
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DOI:
10.2217/17460913.3.5.507
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发表时间:
2008-10-01
影响因子:
3.1
通讯作者:
Hatzakis, A.
Hatzakis, A.
中科院分区:
生物学3区
文献类型:
--
作者:
Nikolopoulos, G.;Paraskevis, D.;Hatzakis, A.

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希腊很早就经历了艾滋病毒/艾滋病对发病率和死亡率的影响。高效抗逆转录病毒疗法的时代缓解了这一流行病的许多后果,然而,艾滋病毒感染仍然是一个极其重要的问题。在希腊,与男性发生性关系的男性是艾滋病毒流行的驱动力,其次是异性感染者,而注射吸毒者的感染率仍处于较低水平。HIV-1分子流行病学研究显示,希腊流行毒株之间存在高度的遗传异质性。与大多数欧洲国家一样,疫情始于B亚型,但近年来,在新诊断的艾滋病毒-1感染者中,A亚型的流行率很高。艾滋病毒需要有效和持续的应对措施,以满足弱势群体的需要。
Greece has experienced early the effect of HIV/AIDS on morbidity and mortality. The era of highly active antiretroviral therapy has alleviated many of the consequences of the epidemic, however, HIV infection remains an issue of utmost significance. Men who have sex with men are the driving force of the HIV epidemic in Greece followed by heterosexually-infected individuals, while infections among injecting drug users remain at low levels. HIV-1 molecular epidemiology studies reveal a high genetic heterogeneity amongst the circulating strains in Greece. The epidemic began with subtype B, as in most of the European countries, however, subtype A was detected at a high prevalence among the newly diagnosed HIV-1-infected individuals in recent years. HIV requires an effective and sustained response meeting the needs of vulnerable subpopulations.