Climbing exercise increases bone mass and trabecular bone turnover through transient regulation of marrow osteogenic and osteoclastogenic potentials in mice

Climbing exercise increases bone mass and trabecular bone turnover through transient regulation of marrow osteogenic and osteoclastogenic potentials in mice
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DOI:
10.1359/jbmr.2003.18.11.2002
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发表时间:
2003-11-01
影响因子:
6.2
通讯作者:
Nakamura, T
Nakamura, T
中科院分区:
医学1区
文献类型:
--
作者:
Mori, T;Okimoto, N;Nakamura, T

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为了探讨骨转换的影响和骨髓细胞在骨细胞中的发育之间的关系,我们建立了小鼠自愿攀爬运动模型。爬坡运动可增加骨髓的骨体积和瞬时成骨潜能。该模型适用于研究机械载荷的力学作用。
To investigate the relationship between the effects of bone turnover and bone marrow cell development in bone cells, we developed a mouse voluntary climbing exercise model. Climbing exercise increased bone volume and transient osteogenic potential of bone marrow. This model would be suitable for investigating the mechanistic roles of mechanical loading.