Clinical manifestations of Q fever in adults and children.
Clinical manifestations of Q fever in adults and children.
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DOI：
10.1016/j.tmaid.2006.06.001
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发表时间：
2007-05-01
影响因子：
12
通讯作者：
Leggat, Peter A
中科院分区：
文献类型：
--
作者：
Terheggen, Ulrich;Leggat, Peter A
Q热是一种常见的人畜共患病，几乎在全球范围内分布，由伯氏柯克斯体引起。农场动物和宠物是主要的感染源，通常通过吸入受污染的气雾剂传播给人类，这些气雾剂可能被风带到远离原始感染源的地方。与农场或野生动物密切相关的职业群体面临的风险最大，但旅行者偶尔会被感染。这种疾病与广泛的临床表现和症状有关，从无症状感染到致命疾病。对这种疾病的认识和新的诊断方法使成人和儿童对各种或多种症状的病例的认识和检测有所增加。然而，儿童似乎较少出现症状，而且可能有较轻微的疾病。这篇对Q热病例的回顾研究了成人和儿童Q热的临床表现和症状，结果表明，与成人相比，急性和慢性Q热儿童的某些症状及其严重程度发生了变化。
Q fever is a common zoonosis with almost a worldwide distribution caused by Coxiella burnetii. Farm animals and pets are the main reservoirs of infection and transmission to humans is usually via inhalation of contaminated aerosols, which may be carried by the wind far from the original source of infection. Occupational groups with close association with farm or wild animals are most at risk, however travellers occasionally become infected. The disease is associated with a wide spectrum of clinical manifestations and symptoms, ranging from asymptomatic infection to fatal disease. Awareness of the disease and newer diagnostic methods led to increase of recognition and detection in cases with various or multiple symptoms in adults and children. However, children seem to be less frequently symptomatic and may have milder disease. This review of Q fever cases examines clinical manifestations and symptoms of Q fever in both adults and children and shows that certain symptoms and their severity have altered presentation in children with acute and chronic Q fever when compared to adults.