Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments.
Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments.
复制标题
DOI：
10.1007/s11306-007-0080-4
复制
发表时间：
2007
期刊：
影响因子：
3.6
通讯作者：
Sauer, Uwe
中科院分区：
文献类型：
--
作者：
van der Werf, Mariet J.;Takors, Ralf;Smedsgaard, Jorn;Nielsen, Jens;Ferenci, Tom;Portais, Jean Charles;Wittmann, Christoph;Hooks, Mark;Tomassini, Alberta;Oldiges, Marco;Fostel, Jennifer;Sauer, Uwe
随着代谢组学作为研究大量不同生物学研究问题的一种手段的日益使用，需要一套最低限度的报告标准，使科学界能够评估、理解、重复、比较和重新调查代谢组学研究。在这里，我们提出了一个最低要求的初稿，以有效地描述涉及微生物或体外生物学对象的代谢组学研究的生物学背景。本建议由代谢组学标准倡议的微生物学和体外生物学工作组与酵母系统生物学网络合作提出，作为代谢组学学会领导的更广泛的标准化倡议的一部分。微生物和体外生物代谢组学被这个工作组定义为对任何细胞或有机体的研究，这些细胞或有机体需要特定的外部介质来促进生长和繁殖。已经定义了代谢组学实验的最小集合和最佳实践集合的报告标准。微生物或体外生物代谢组学实验的最小报告标准集包括代谢组学实验所特有的、关键决定实验结果的那些因素。最佳实践报告标准集既包含代谢组学实验特有的因素，也包含关键决定任何微生物或体外生物实验结果的一般方面。
With the increasing use of metabolomics as a means to study a large number of different biological research questions, there is a need for a minimal set of reporting standards that allow the scientific community to evaluate, understand, repeat, compare and re-investigate metabolomics studies. Here we propose, a first draft of minimal requirements to effectively describe the biological context of metabolomics studies that involve microbial or in vitro biological subjects. This recommendation has been produced by the microbiology and in vitro biology working subgroup of the Metabolomics Standards Initiative in collaboration with the yeast systems biology network as part of a wider standardization initiative led by the Metabolomics Society. Microbial and in vitro biology metabolomics is defined by this sub-working group as studies with any cell or organism that require a defined external medium to facilitate growth and propagation. Both a minimal set and a best practice set of reporting standards for metabolomics experiments have been defined. The minimal set of reporting standards for microbial or in vitro biology metabolomics experiments includes those factors that are specific for metabolomics experiments and that critically determine the outcome of the experiments. The best practice set of reporting standards contains both the factors that are specific for metabolomics experiments and general aspects that critically determine the outcome of any microbial or in vitro biological experiment.
登录
查看更多内容
影响因子：
46.9
作者：
Jenkins, H;Hardy, N;Kell, DB
通讯作者：
Kell, DB
影响因子：
3.3
作者：
Field, Dawn;Morrison, Norman;Sterk, Peter
通讯作者：
Sterk, Peter
影响因子：
2.6
作者：
Villas-Bôas, SG;Hojer-Pedersen, J;Nielsen, J
通讯作者：
Nielsen, J
影响因子：
3.8
作者：
Fostel, J;Choi, D;Waters, M
通讯作者：
Waters, M
影响因子：
7.4
作者：
Jenkins, H;Johnson, H;Hardy, N
通讯作者：
Hardy, N