Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988-2012.
Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988-2012.
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DOI：
10.5888/pcd14.160287
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发表时间：
2017-03-16
影响因子：
5.5
通讯作者：
Akinyemiju T
中科院分区：
文献类型：
--
作者：
Moore JX;Chaudhary N;Akinyemiju T
代谢综合征是一组与多种慢性疾病（包括癌症和心血管疾病）风险增加相关的心脏代谢危险因素。本研究的目的是根据种族和性别估计代谢综合征的总体患病率，并评估1988年至2012年的患病率趋势。我们分析了1988年至2012年国家健康和营养检查调查（NHANES）的数据。我们将代谢综合征定义为至少存在以下3种成分：腰围升高、甘油三酯升高、高密度脂蛋白胆固醇降低、高血压和空腹血糖升高。分析了1988-1994年、1999-2006年和2007-2012年三个时期的数据。在美国18岁及以上的成年人中，从1988-1994年到2007-2012年，代谢综合征的患病率上升了35%以上，从25.3%上升到34.2%。2007-2012年期间，非西班牙裔黑人男性患代谢综合征的可能性低于非西班牙裔白人男性（优势比[OR]， 0.77； 95%可信区间[CI]， 0.66-0.89）。然而，非西班牙裔黑人妇女比非西班牙裔白人妇女更容易患代谢综合征（OR, 1.20; 95% CI, 1.02-1.40）。2007-2012年期间，低教育水平（OR, 1.56; 95% CI, 1.32-1.84）和高龄（OR, 1.73; 95% CI, 1.67-1.80）与代谢综合征的可能性增加独立相关。从1988年到2012年，每个社会人口群体的代谢综合征患病率都有所增加；到2012年，超过三分之一的美国成年人符合几个国际组织共同商定的代谢综合征的定义和标准。
Metabolic syndrome is a cluster of cardiometabolic risk factors associated with increased risk of multiple chronic diseases, including cancer and cardiovascular disease. The objectives of this study were to estimate the prevalence of metabolic syndrome overall, by race and sex, and to assess trends in prevalence from 1988 through 2012. We analyzed data from the National Health and Nutrition Examination Survey (NHANES) for 1988 through 2012. We defined metabolic syndrome as the presence of at least 3 of these components: elevated waist circumference, elevated triglycerides, reduced high-density lipoprotein cholesterol, high blood pressure, and elevated fasting blood glucose. Data were analyzed for 3 periods: 1988–1994, 1999–2006, and 2007–2012. Among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%. During 2007–2012, non-Hispanic black men were less likely than non-Hispanic white men to have metabolic syndrome (odds ratio [OR], 0.77; 95% confidence interval [CI], 0.66–0.89). However, non-Hispanic black women were more likely than non-Hispanic white women to have metabolic syndrome (OR, 1.20; 95% CI, 1.02–1.40). Low education level (OR, 1.56; 95% CI, 1.32–1.84) and advanced age (OR, 1.73; 95% CI, 1.67–1.80) were independently associated with increased likelihood of metabolic syndrome during 2007–2012. Metabolic syndrome prevalence increased from 1988 to 2012 for every sociodemographic group; by 2012, more than a third of all US adults met the definition and criteria for metabolic syndrome agreed to jointly by several international organizations.