Synthesis of a globotetraose trimer
Synthesis of a globotetraose trimer
复制标题
DOI：
10.1016/s0008-6215(02)00080-0
复制
发表时间：
2002-05-13
影响因子：
3.1
通讯作者：
Nilsson, UJ
中科院分区：
文献类型：
--
作者：
Bergh, A;Bhattacharyya, S;Nilsson, UJ
描述了通过三（2 - 氨乙基）胺与球四糖的疏水性方酸癸酯糖苷反应，以74%的产率合成球四糖三聚体。该合成过程易于用反相高效液相色谱监测和纯化。未反应的方酸癸酯球四糖苷被回收，使得该方法极具经济性。（C）2002爱思唯尔科学有限公司。保留所有权利。
The synthesis is described of a globotetraose trimer in 74% yield by the reaction of tris(2-aminoethyl)amine with the hydrophobic squaric decyl ester glycoside of globotetraose. The synthesis was readily monitored and purified using reversed phase HPLC. Unreacted squaric decyl ester globotetraoside was recovered rendering the method highly economical. (C) 2002 Elsevier Science Ltd. All rights reserved.