Spatially filtered magnetoencephalography compared with electrocorticography to identify intrinsically epileptogenic focal cortical dysplasia
Spatially filtered magnetoencephalography compared with electrocorticography to identify intrinsically epileptogenic focal cortical dysplasia
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DOI：
10.1016/j.eplepsyres.2008.06.006
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发表时间：
2008-10-01
影响因子：
2.2
通讯作者：
Otsubo, Hiroshi
中科院分区：
文献类型：
--
作者：
Ishii, Ryouhei;Canuet, Leonides;Otsubo, Hiroshi
本研究旨在探讨脑磁图(MEG)空间滤波源定位技术合成孔径磁测峰度(SAM(g(2)在定位局灶性皮质发育不良(FCD)致痫灶中的作用。对3例FCD患儿进行了发作期起始区(IOZ)定位研究。所有患者随后都进行了手术外皮质脑电图(ECoG)以治疗顽固性癫痫，并进行了手术切除。SAM(G2)分析显示，所有儿童的发作间期脑电刺激源与ECoG上的IOZ重叠。我们建议对致痫的FCD患者进行MEG-SAM(g(2))和MEG发作间期棘波来源定位。(C)2008爱思唯尔B.V.保留所有权利。
This study was carried out to evaluate Synthetic Aperture Magnetometry-kurtosis (SAM(g(2))), a spatially filtered source localization technique in magnetoencephalography (MEG), for identification of epileptogenic areas of focal cortical dysplasia (FCD). Three children with FCD were investigated to localize the ictal onset zone (IOZ). All patients subsequently had extra-operative electrocorticography (ECoG) for intractable epilepsy and surgical resection. SAM(g2) analysis showed overlapping of interictal MEG spike sources with the IOZ on ECoG in all children. We recommend MEG-SAM(g(2)) and MEG interictal spike source localization in patients with epileptogenic FCD. (C) 2008 Elsevier B.V. All rights reserved.