Prevalence of autism spectrum disorder and autistic traits in children with anorexia nervosa and avoidant/restrictive food intake disorder.
Prevalence of autism spectrum disorder and autistic traits in children with anorexia nervosa and avoidant/restrictive food intake disorder.
复制标题
DOI：
10.1186/s13030-021-00212-3
复制
发表时间：
2021-05-17
影响因子：
2.1
通讯作者：
Sakuta R
中科院分区：
文献类型：
--
作者：
Inoue T;Otani R;Iguchi T;Ishii R;Uchida S;Okada A;Kitayama S;Koyanagi K;Suzuki Y;Suzuki Y;Sumi Y;Takamiya S;Tsurumaru Y;Nagamitsu S;Fukai Y;Fujii C;Matsuoka M;Iwanami J;Wakabayashi A;Sakuta R
自闭症谱系障碍（ASD）和进食障碍（FED），如神经性厌食症（AN）密切相关，如频繁的合并症和重叠特征所证明的。然而，饮食和社交行为是由文化塑造的，因此研究不同人群中的这些关联至关重要。此外，FED是异质性的，并且没有对回避/限制性食物摄入障碍（ARFID）中的自闭症特征进行检查。因此，我们采用自闭症谱系商儿童版（AQC）和儿童饮食态度测试（ChEAT 26），从一项前瞻性多中心队列研究中调查了患有AN（n = 92）或ARFID（n = 32）的日本儿童中ASD和自闭症特征的患病率。ASD患病率在AN和ARFID中均较高（分别为16.3%和12.5%）。AN组在所有AQC子量表上的得分均显著高于年龄匹配的健康对照（HC）组，但AQC得分与ChEAT 26得分之间无显著相关性。在AFRID组中，AQC评分与HC没有差异，但AQC总分与ChEAT 26评分之间以及几个AQC与ChEAT 26分量表之间存在显著相关性。AN和ARFID组ASD的患病率都很高。AN组表现出显着更高程度的自闭症特征比HC组，但是，没有发现ARFID和HC组之间的差异。临床医生在治疗ED儿童时需要了解这些比率。在线版本包含补充材料，可在10.1186/s13030-021-00212-3获得。
Autism spectrum disorder (ASD) and feeding and eating disorders (FEDs) such as anorexia nervosa (AN) are strongly linked as evidenced by frequent comorbidity and overlapping traits. However, eating and social behaviors are shaped by culture, so it is critical to examine these associations in different populations. Moreover, FEDs are heterogeneous, and there has been no examination of autistic traits in avoidant/restrictive food intake disorder (ARFID). Therefore, we investigated the prevalence of ASD and autistic traits among Japanese children with AN (n = 92) or ARFID (n = 32) from a prospective multicenter cohort study using the Autism Spectrum Quotient Children’s version (AQC) and Children’s Eating Attitudes Test (ChEAT26). ASD prevalence was high in both AN and ARFID (16.3 and 12.5%, respectively). The AN group exhibited significantly higher scores on all AQC subscales than an age-matched healthy control (HC) group, but there were no significant correlations between AQC scores and ChEAT26 scores. In the AFRID group, AQC scores did not differ from HCs, but significant correlations were found between total AQC and ChEAT26 scores and between several AQC and ChEAT26 subscales. Both the AN and ARFID groups had high prevalence rates of ASD. The AN group showed a significantly higher degree of autistic traits than the HC group; however, no difference was found between the ARFID and HC groups. Clinicians need to be aware of these rates when working with children with ED. The online version contains supplementary material available at 10.1186/s13030-021-00212-3.
登录
查看更多内容
影响因子：
3.2
作者：
Calderoni S;Fantozzi P;Balboni G;Pagni V;Franzoni E;Apicella F;Narzisi A;Maestro S;Muratori F
通讯作者：
Muratori F
影响因子：
3.2
作者：
Calderoni S;Fantozzi P;Maestro S;Brunori E;Narzisi A;Balboni G;Muratori F
通讯作者：
Muratori F
影响因子：
6.9
作者：
Hoek, Hans Wijbrand
通讯作者：
Hoek, Hans Wijbrand
影响因子：
10.5
作者：
Baron-Cohen, Simon;Scott, Fiona J.;Brayne, Carol
通讯作者：
Brayne, Carol
影响因子：
2.8
作者：
GILLBERG, C;RASTAM, M
通讯作者：
RASTAM, M