Xenoestrogens released from lacquer coatings in food cans.
Xenoestrogens released from lacquer coatings in food cans.
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DOI：
10.1289/ehp.95103608
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发表时间：
1995-06
影响因子：
10.4
通讯作者：
Olea N
中科院分区：
文献类型：
--
作者：
Brotons JA;Olea-Serrano MF;Villalobos M;Pedraza V;Olea N
我们目前的数据表明，一些食品保存在漆涂层罐和液体，他们可能获得雌激素活性。使用E-screen生物测定法测量激素活性。罐装蔬菜的生物活性是制造容器时使用的塑料单体的结果。塑料单体双酚A，通过质谱法鉴定，不仅在腌制蔬菜的液体中，而且在罐中高压灭菌的水中被发现为污染物。提取物中双酚A的量占所有测量的激素活性。虽然不能排除其他异种雌激素的存在，但很明显，这些罐中的所有雌激素活性都是由于从漆涂层中浸出的双酚A所致。在食品包装材料中使用塑料可能需要更仔细的审查，以确定环氧树脂和聚碳酸酯是否有助于人类暴露于异种雌激素。
We present data showing that some foods preserved in lacquer-coated cans and the liquid in them may acquire estrogenic activity. Hormonal activity was measured using the E-screen bioassay. The biological activity of vegetables packed in cans was a result of plastic monomers used in manufacturing the containers. The plastic monomer bisphenol-A, identified by mass spectrometry, was found as a contaminant not only in the liquid of the preserved vegetables but also in water autoclaved in the cans. The amount of bisphenol-A in the extracts accounted for all the hormonal activity measured. Although the presence of other xenoestrogens cannot be ruled out, it is apparent that all estrogenic activity in these cans was due to bisphenol-A leached from the lacquer coating. The use of plastic in food-packaging materials may require closer scrutiny to determine whether epoxy resins and polycarbonates contribute to human exposure to xenoestrogens.