Atypical rapid audio-visual temporal recalibration in autism spectrum disorders
Atypical rapid audio-visual temporal recalibration in autism spectrum disorders
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DOI：
10.1002/aur.1633
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发表时间：
2017-01-01
期刊：
影响因子：
4.7
通讯作者：
Wallace, Mark T.
中科院分区：
文献类型：
--
作者：
Noel, Jean-Paul;De Niear, Matthew A.;Wallace, Mark T.
感觉和多感觉功能的变化越来越被认为是自闭症谱系障碍（ASD）的常见表型特征。此外，最近的许多证据表明，感觉障碍可能在导致社交沟通障碍（自闭症谱系障碍的核心诊断特征之一）方面发挥重要作用。在ASD中观察到的既定感觉障碍是视听时间敏锐度降低。在目前的研究中，我们大大扩展了这些探索的多感官时间功能的框架内，无法迅速重新校准视听时间关系的变化可能会发挥重要的和未被充分认识的作用，在ASD。在范式中，我们提出了ASD和典型发展（TD）的儿童和青少年与异步视听刺激的不同程度的复杂性，并要求他们执行的一致性判断（SJ）。在批判性分析中，我们测试视听时间处理的审判t作为审判t-1的条件。结果表明，对于简单和非语言刺激，ASD个体不能以与TD对应者相同的方式快速重新校准到视听刺激（即，闪光和嘟嘟声、手持工具），但对于语音刺激表现出相当快的重新校准。这些结果进行了讨论，在以前的工作中，显示语音特定的视听时间功能的缺陷，在ASD，并在目前的理论自闭症集中在感官噪声和稳定的感知表征。Autism Res2017，10：121-129. (c)2016年国际自闭症研究学会，Wiley Periodicals，Inc。
Changes in sensory and multisensory function are increasingly recognized as a common phenotypic characteristic of Autism Spectrum Disorders (ASD). Furthermore, much recent evidence suggests that sensory disturbances likely play an important role in contributing to social communication weaknessesone of the core diagnostic features of ASD. An established sensory disturbance observed in ASD is reduced audiovisual temporal acuity. In the current study, we substantially extend these explorations of multisensory temporal function within the framework that an inability to rapidly recalibrate to changes in audiovisual temporal relations may play an important and under-recognized role in ASD. In the paradigm, we present ASD and typically developing (TD) children and adolescents with asynchronous audiovisual stimuli of varying levels of complexity and ask them to perform a simultaneity judgment (SJ). In the critical analysis, we test audiovisual temporal processing on trial t as a condition of trial t-1. The results demonstrate that individuals with ASD fail to rapidly recalibrate to audiovisual asynchronies in an equivalent manner to their TD counterparts for simple and non-linguistic stimuli (i.e., flashes and beeps, hand-held tools), but exhibit comparable rapid recalibration for speech stimuli. These results are discussed in terms of prior work showing a speech-specific deficit in audiovisual temporal function in ASD, and in light of current theories of autism focusing on sensory noise and stability of perceptual representations. Autism Res2017, 10: 121-129. (c) 2016 International Society for Autism Research, Wiley Periodicals, Inc.