Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar
Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar
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DOI：
10.1128/aac.01459-07
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发表时间：
2008-07-01
影响因子：
4.9
通讯作者：
White, Nicholas J.
中科院分区：
文献类型：
--
作者：
Imwong, Mallika;Pukrittayakamee, Sasithon;White, Nicholas J.
Plasmodium vivax mdr1 gene amplification, quantified by real-time PCR, was significantly more common on the western Thailand border (6 of 66 samples), where mefloquine pressure has been intense, than elsewhere in southeast Asia (3 of 149; P = 0.02). Five coding mutations in pvmdr1, independent of gene amplification, were also found.
