Functional universality and evolutionary diversity: insights from the structure of the ribosome.
Functional universality and evolutionary diversity: insights from the structure of the ribosome.
复制标题
功能普遍性和进化多样性：来自核糖体结构的见解。
DOI：
10.1016/s0969-2126(98)00069-0
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Franceschi,F
中科院分区：
文献类型：
--
作者：
Yonath,A;Franceschi,F
以25倍分辨率重建的哺乳动物核糖体的结构为我们目前的知识增加了一个新的维度，因为它体现了核糖体在蛋白质生物合成中的主要任务方面的保守性和普遍性。利用x射线晶体学和电子显微镜对核糖体进行联合研究，可能会进一步提高我们对核糖体功能的理解。
The structure of the mammalian ribosome, reconstructed at 25 å resolution, has added a new dimension to our current knowledge, as it manifests the conservation and universality of the ribosome in respect to its primary tasks in protein biosynthesis. A combined approach to study of the ribosome, using X-ray crystallography and electron microscopy, may further improve our understanding of ribosome function in the future.