A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System.
A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System.
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DOI：
10.3390/s17020280
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发表时间：
2017-01-31
期刊：
影响因子：
--
通讯作者：
Holder D
中科院分区：
文献类型：
--
作者：
Avery J;Dowrick T;Faulkner M;Goren N;Holder D
一个高度通用的电阻抗断层成像（EIT）系统，昵称为ScouseTom，已经开发出来。该系统允许控制电流幅度、频率、电极数量、注射方案和数据处理。使用Keithley 6221电流源注入电流，并使用最小带宽为3.2 kHz的24位EEG系统记录电压。定制PCB与PC连接，以控制测量过程、电极寻址和外部刺激的触发。该系统的性能的特点是使用电阻幻影代表人类头皮记录，与77.5 dB的SNR，稳定在四个小时的记录和20 Hz至20 kHz。在使用头皮电极进行的出血研究和使用大鼠皮层电极垫进行的诱发活动研究中，有可能在已知的发病区域重建与已建立文献匹配的图像。使用人体头皮电极收集的数据与已知的组织阻抗谱相匹配，并且在频率范围内保持稳定。实验过程是软件控制的，并且很容易适应新的范例。在可能的情况下，使用商业或开源组件，以尽量减少复制的复杂性。该系统的硬件设计和软件已根据开放源码许可证发布，鼓励各方作出贡献，并允许迅速复制。
A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and voltages are recorded with a 24-bit EEG system with minimum bandwidth of 3.2 kHz. Custom PCBs interface with a PC to control the measurement process, electrode addressing and triggering of external stimuli. The performance of the system was characterised using resistor phantoms to represent human scalp recordings, with an SNR of 77.5 dB, stable across a four hour recording and 20 Hz to 20 kHz. In studies of both haeomorrhage using scalp electrodes, and evoked activity using epicortical electrode mats in rats, it was possible to reconstruct images matching established literature at known areas of onset. Data collected using scalp electrode in humans matched known tissue impedance spectra and was stable over frequency. The experimental procedure is software controlled and is readily adaptable to new paradigms. Where possible, commercial or open-source components were used, to minimise the complexity in reproduction. The hardware designs and software for the system have been released under an open source licence, encouraging contributions and allowing for rapid replication.
影响因子：
3.2
作者：
Packham B;Barnes G;Dos Santos GS;Aristovich K;Gilad O;Ghosh A;Oh T;Holder D
通讯作者：
Holder D