A 4-year study of the mycological aspects of Kashin-Beck disease in Tibet
A 4-year study of the mycological aspects of Kashin-Beck disease in Tibet
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DOI：
10.1007/s002640000218
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发表时间：
2001-06-01
影响因子：
2.7
通讯作者：
Haubruge, E
中科院分区：
文献类型：
--
作者：
Chasseur, C;Suetens, C;Haubruge, E
为了弄清食品中产生真菌毒素的真菌与大骨节病（KBD）之间的关系，我们检测了大骨节病流行地区受影响家庭和未受影响家庭大麦籽粒样品中真菌的发生和污染水平。以未发生大骨节病的对照区为参照。1995年获得的第一批结果表明，大麦籽粒中嗜温真菌污染总量在大骨节病家庭中始终较高。玫瑰毛癣菌（Trichothecium roseum, Pers） Link ex gray，伊藤dreschleera Ito和Alternaria Nees ex fr是三种与大骨节病显著相关的最常见真菌。1996年，我们再次观察到受影响和未受影响的家庭之间的显著差异，特别是在玫瑰毛霉和普鲁斯乌洛克兰。在此基础上，提出了防治大骨节病的措施，并于1998年在20个新村建立了防治方案。
In order to clarify the association between mycotoxin-producing fungi in food and Kashin-Beck disease (KBD), we examined the occurrence and contamination levels of fungi in samples of barley grain, from KBD-affected families and from unaffected families in endemic areas. A control area without the occurrence of KBD served as reference. The first results obtained in 1995 showed that total mesophilic fungal contamination of barley grain was consistently higher in families with KBD. Trichothecium roseum (Pers) Link ex gray, Dreschlera Ito and Alternaria Nees ex Fr. were the three most common fungi significantly associated with KBD. In 1996 we again observed a significant difference between affected and non-affected families, especially with Trichothecium roseum and Ulocladium Preuss. On this basis, measures to prevent KBD were suggested and a preventive program has been set up since 1998 in 20 new villages.