Maternally inherited male-killing microorganisms may confound interpretation of mitochondrial DNA variability
Maternally inherited male-killing microorganisms may confound interpretation of mitochondrial DNA variability
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DOI：
10.1111/j.1095-8312.1996.tb01446.x
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发表时间：
1996-08-01
影响因子：
1.9
通讯作者：
Hurst, GDD
中科院分区：
文献类型：
--
作者：
Johnstone, RA;Hurst, GDD
线粒体DNA的变化通常用于追踪种群和物种的进化史。我们在这里讨论用细胞质遗传的男性致死共生体对线粒体基因组进化的影响。当杀死雄性宿主时，男性致命的共生体扩散，增加了同胞女宿主的生殖成功。来自带有男性杀手的个体的女儿的生存率增加将产生与男性杀手相关的米蒂型频率的增加。如果微生物的水平传播稀有并且人口大小不是很小，那么微生物和特定的mitytypes之间的连锁不平衡将导致人群内部的线粒体变异性繁殖，这都是因为在这种微生物，这种微生物的蔓延期间都有选择性扫描并处于平衡状态。因此，男性杀死的共生体可能将mtDNA变异性混淆在人口参数的估计中。我们讨论了男性杀手和细胞质不相容的诱导共生wolbachia之间的差异，以及共生体存在对种群之间基因流量的估计的可能性也可能会混淆。 （c）1996伦敦林尼亚学会
Variation in mitochondrial DNA is often used to trace the evolutionary history of populations and species. We here discuss the effect of infection with cytoplasmically inherited male-lethal symbionts on mitochondrial genome evolution. Male-lethal symbionts spread when killing male hosts increases the lifetime reproductive success of sibling female hosts. This increase in the survivorship of daughters from individuals bearing a male-killer will produce a concomitant increase in the frequency of mitotypes associated with the male-killer. If horizontal transmission of the microoorganism is rare and population sizes not very small, then linkage disequilibrium between microorganism and particular mitotypes will result in a reproduction of within-population mitochondrial variability both because of a selective sweep during the spread of such a micro-organism, and also at equilibrium. Male-killing symbionts may thus confound the use of mtDNA variability in estimation of population parameters. We discuss the differences between the effects of male-killers and the cytoplasmic incompatibility-inducing symbiont Wolbachia, and the possibility that estimation of gene flow between populations may also be confounded by symbiont presence. (C) 1996 The Linnean Society of London