The Challenges of Integrating Oxidative Stress into Life-history Biology
The Challenges of Integrating Oxidative Stress into Life-history Biology
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DOI：
10.1525/bio.2011.61.3.5
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发表时间：
2011-03-01
期刊：
影响因子：
10.1
通讯作者：
Uller, Tobias
中科院分区：
文献类型：
--
作者：
Isaksson, Caroline;Sheldon, Ben C.;Uller, Tobias
有人提出，调节生物功能的分子和生理系统施加了成本和约束，这是理解生活史变化的基础。特别是，氧化应激的研究强调了进化偶然性如何对生物体施加新的权衡，以及这如何可能创造或消除性状之间的功能联系。在这里，我们批判性地评估这些主张的概念和经验基础，以及它们对生活史变异研究的意义。两个关键的挑战是超越目前对调控系统单一组成部分的关注，在单一时间点进行评估，并确定性状和阶段特定的营养需求对生活史性状之间功能联系的重要性。此外，未来的进展将严重依赖于在自然环境中复制实验室研究，以针对野生环境中权衡调节的复杂性。
It has been proposed that the molecular and physiological systems that regulate biological functions impose costs and constraints that are fundamental to the understanding of variation in life histories. In particular, studies of oxidative stress emphasize how evolutionary contingency can impose novel trade-offs for organisms, and how this may create or eliminate functional linkages between traits. Here, we critically assess the conceptual and empirical basis for these claims and what they mean for the study of life-history variation. Two key challenges are to go beyond the current focus on single components of regulatory systems, assessed at single points in time, and to establish the importance of trait- and stage-specific nutrient requirements for the functional linkage between life-history traits. Furthermore, future progress will critically depend on the replication of laboratory studies in natural settings to target the complexity of trade-off regulation in the wild.