Refractory hypoglycemia controlled by systemic chemotherapy with advanced hepatocellular carcinoma: A case report
Refractory hypoglycemia controlled by systemic chemotherapy with advanced hepatocellular carcinoma: A case report
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DOI：
10.3892/ol.2015.3915
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发表时间：
2016-01-01
期刊：
影响因子：
2.9
通讯作者：
Chang, Pei-Hung
中科院分区：
文献类型：
--
作者：
Huang, Jen-Seng;Chang, Pei-Hung
非胰岛细胞瘤低血糖症是一种罕见但严重的恶性肿瘤并发症。NICTH患者可能因潜在肿瘤而出现不适，特别是当低血糖的机制是肝脏中广泛的肿瘤负荷时。据报道，肝细胞癌（HCC）是NICTH的第二大常见原因。用于治疗NICTH的治疗策略包括减少肿瘤质量或肿瘤负荷，以及如果治疗尝试失败则对症状进行姑息治疗。在本研究中，我们报告了一位晚期肝癌患者，采用全身化疗成功地控制了低血糖，该患者表现为难治性NICTH。
Non-islet cell tumor hypoglycemia (NICTH) is an uncommon but serious complication of malignancy. Patients with NICTH may appear unwell due to the underlying tumor, particularly when the mechanism of hypoglycemia is extensive tumor burden in the liver. Hepatocellular carcinoma (HCC) is reported to be the second most common cause of NICTH. The therapeutic strategies used in treating NICTH involve reduction of the tumor mass or tumor load, and palliative treatment of symptoms if curative attempts fail. In the present study we report the successful control of hypoglycemia using systemic chemotherapy in an advanced HCC patient who presented with refractory NICTH.