A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study.
A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study.
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DOI：
10.1001/archinte.1991.00400050081016
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发表时间：
1991-05
影响因子：
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通讯作者：
F. Anderson;H. Wheeler;R. Goldberg;D. Hosmer;N. Patwardhan;B. Jovanovic;Ann Forcier;J. Dalen
中科院分区：
文献类型：
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作者：
F. Anderson;H. Wheeler;R. Goldberg;D. Hosmer;N. Patwardhan;B. Jovanovic;Ann Forcier;J. Dalen
一项社区范围的研究在马萨诸塞州伍斯特市的 16 家短期住院医院进行，旨在调查 1985 年 7 月 1 日至 1986 年 12 月 31 日期间住院患者的深静脉血栓和肺栓塞的发病率和病死率。仅深静脉血栓的年平均发病率为每 10 万人中 48 例，而伴或不伴深静脉血栓的肺栓塞的发病率为每 10 万人中 23 例。 100,000。随着年龄的增长，深静脉血栓和肺栓塞的发生率呈指数增加。静脉血栓栓塞的院内病死率为12%。出院患者中，出院后1、2、3年的长期病死率分别为19%、25%和30%。根据这项基于人群的研究数据推断，美国每年在短期医院接受治疗的患者中约有 170,000 例临床公认的静脉血栓栓塞新病例，并且有 99,000 例因疾病复发而住院。由于这种疾病的隐匿性和美国尸检率较低，静脉血栓栓塞的总发病率、患病率和死亡率仍然难以捉摸。
A community-wide study was conducted in 16 short-stay hospitals in metropolitan Worcester, Mass, to examine the incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism in patients hospitalized between July 1, 1985, and December 31, 1986. The average annual incidence of deep vein thrombosis alone was 48 per 100,000, while the incidence of pulmonary embolism with or without deep vein thrombosis was 23 per 100,000. The incidence rates of deep vein thrombosis and pulmonary embolism increased exponentially with age. The in-hospital case-fatality rate of venous thromboembolism was 12%. Among patients discharged from the hospital, the long-term case-fatality rates were 19%, 25%, and 30% at 1, 2, and 3 years after hospital discharge. Extrapolation of the data from this population-based study suggests that there are approximately 170,000 new cases of clinically recognized venous thromboembolism in patients treated in short-stay hospitals in the United States each year, and 99,000 hospitalizations for recurrent disease. Because of the silent nature of this disease and the low rate of autopsy in the United States, the total incidence, prevalence, and mortality rates of venous thromboembolism remain elusive.