Localizing EEG Recordings Associated With a Balance Threat During Unexpected Postural Translations in Young and Elderly Adults.
Localizing EEG Recordings Associated With a Balance Threat During Unexpected Postural Translations in Young and Elderly Adults.
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DOI：
10.1109/tnsre.2023.3331211
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发表时间：
2023
影响因子：
4.9
通讯作者：
Keshner, Emily A.
中科院分区：
文献类型：
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作者：
Wang, Zhuo;Graci, Valentina;Seacrist, Thomas;Guez, Allon;Keshner, Emily A.
关键词：
平衡扰动伴随着全局皮层激活，当姿势扰动是意外的时，其幅度增加，可能是由于增加了惊吓反应。一个具体的网站，最好的记录反应意外不稳定尚未确定。我们假设，位于皮层下脑干机制附近的单个传感器可以作为对不可预测的姿势事件的反应的标记。20名健康青年（20.8 ± 2.9岁）和20名健康老年人（71.7 ± 4.2岁）在动态平台上直立睁眼。在后（29次试模）和前（5次捕获试模）方向上输送平台平移（20 cm，100 cm/s）。活动EEG电极位于Fz和Cz以及双侧乳突上。在平台加速度开始后，对来自每次试验的300 ms EEG活动进行去趋势化、基线校正，并标准化为第一次试验。计算每个通道的“不可预测”和“可预测”事件的平均均方根（RMS）值。EEG RMS反应在不可预测的干扰下显著大于可预测的干扰：Cz（p<0.001）、Fz（p<0.003）和乳突（p<0.0001）。在Cz（p<0.02）和乳突（p<0.04），老年人的EEG RMS反应也显著高于年轻人。性别对乳突感觉器反应的显著影响（p<0.04）表明，老年男性成年人是年龄效应的主要原因。这些结果证实，皮质活动所造成的一个意想不到的姿势障碍，可以描绘一个单一的传感器位于乳突骨在年轻人和老年人。
Balance perturbations are accompanied by global cortical activation that increases in magnitude when postural perturbations are unexpected, potentially due to the addition of a startle response. A specific site for best recording the response to unexpected destabilization has not been identified. We hypothesize that a single sensor located near to subcortical brainstem mechanisms could serve as a marker for the response to unpredictable postural events. Twenty healthy young (20.8 ± 2.9 yrs) and 20 healthy elder (71.7 ± 4.2 yrs) adults stood upright on a dynamic platform with eyes open. Platform translations (20 cm at 100 cm/s) were delivered in the posterior (29 trials) and anterior (5 catch trials) directions. Active EEG electrodes were located at Fz and Cz and bilaterally on the mastoids. Following platform acceleration onset, 300 ms of EEG activity from each trial was detrended, baseline-corrected, and normalized to the first trial. Average Root-Mean-Square (RMS) values across “unpredictable” and “predictable” events were computed for each channel. EEG RMS responses were significantly greater with unpredictable than predictable disturbances: Cz (p<0.001), Fz (p<0.003), and mastoid (p<0.0001). EEG RMS responses were also significantly greater in elderly than young adults at Cz (p<0.02) and mastoid (p<0.04). A significant effect of sex in the responses at the mastoid sensors (p<0.04) revealed that elderly male adults were principally responsible for the age effect. These results confirm that the cortical activity resulting from an unexpected postural disturbance could be portrayed by a single sensor located over the mastoid bone in both young and elderly adults.