Neonatal necrotizing enterocolitis: Clinical challenges, pathophysiology and management.
Neonatal necrotizing enterocolitis: Clinical challenges, pathophysiology and management.
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DOI：
10.1016/j.pathophys.2013.11.009
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发表时间：
2014-02-01
期刊：
影响因子：
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通讯作者：
Pramanik, Arun
中科院分区：
文献类型：
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作者：
Huda, Shehzad;Chaudhery, Shabnum;Pramanik, Arun
由于NEC的高发病率和死亡率，它仍然是外科医生、外科医生和胃肠病学家的主要关注点。这些婴儿往往发育不良，并造成重大的经济负担，导致这些家庭的显着压力。通过制定和坚持严格的喂养方案，鼓励母乳喂养，最好是从婴儿的母亲，使用益生菌，明智的抗生素使用，制定输血方案，NEC的发生可能会减少。然而，由于其多因素的病因，它不能完全根除在新生儿重症监护病房，特别是在极早产儿。对NEC和质量改进项目的持续监督可能是有益的。
NEC remains a major concern for neonatologists, surgeons, and gastroenterologists due to its high morbidity and mortality. These infants often have poor developmental outcome, and contribute to significant economic burden resulting in marked stress in these families. By developing and adhering to strict feeding protocols, encouraging human milk feeding preferably from the infant's mother, use of probiotics, judicious antibiotic use, instituting blood transfusion protocols, the occurrence of NEC may possibly be reduced. However, because of its multifactorial etiology, it cannot be completely eradicated in the NICUs, particularly in the extremely premature infants. Ongoing surveillance of NEC and quality improvement projects may be beneficial.