An attentional inhibitory deficit for irrelevant information in obsessive-compulsive disorder: Evidence from ERPs
An attentional inhibitory deficit for irrelevant information in obsessive-compulsive disorder: Evidence from ERPs
复制标题
强迫症患者对不相关信息的注意力抑制缺陷：来自 ERP 的证据
DOI：
10.1016/j.ijpsycho.2014.11.002
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发表时间：
2014-12-01
影响因子：
3
通讯作者：
Liu, Wanting
中科院分区：
文献类型：
--
作者：
Fan, Jie;Zhong, Mingtian;Liu, Wanting
以往关于注意偏向的研究表明，强迫症（OCD）患者对各种刺激的反应时（RT）总体上较长。据推测，这种普遍的缓慢可能表明存在注意力抑制缺陷的强迫症。为了验证这一假设，事件相关电位（ERP）记录在31个非药物强迫症患者和29个年龄，利手和性别匹配的健康对照，而他们进行了情绪Stroop任务（EST）。与对照组相比，强迫症患者对消极词的干扰效应相似，但对所有词的反应时延长，P2和P3波幅增大。这些结果支持了强迫症的特点是对无关信息的注意抑制功能障碍的观点。(C)© 2014 Elsevier B.V.保留所有权利。
Previous studies on attentional bias have demonstrated that patients with obsessive-compulsive disorder (OCD) have an overall longer reaction time (RT) for various stimuli. It was hypothesized that this general slowness may indicate the presence of an attentional inhibition deficit in OCD. To test the hypothesis, event-related potentials (ERPs) were recorded in 31 non-medicated OCD patients and 29 age-, handedness- and sex-matched healthy controls while they performed an emotional Stroop task (EST). Relative to the control subjects, the OCD patients had similar interference effects for negative words, but an overall longer RT and larger P2 and P3 amplitudes to all words. These results support the notion that OCD is characterized by an attentional inhibitory dysfunction for irrelevant information. (C) 2014 Elsevier B.V. All rights reserved.