Myocardial infarction in Swedish subway drivers

Myocardial infarction in Swedish subway drivers
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DOI:
10.5271/sjweh.1142
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发表时间:
2007-08-01
影响因子:
6.3
通讯作者:
Gustavsson, Per
Gustavsson, Per
中科院分区:
医学2区
文献类型:
--
作者:
Bigert, Carolina;Klerdal, Kristina;Gustavsson, Per

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城市空气中的颗粒物与普通人群发生心肌梗死的风险相关。在斯德哥尔摩和其他几个大城市的地铁系统中检测到非常高水平的空气颗粒。这种情况引起了地铁工作人员对健康的负面影响的担忧。这项研究的目的是调查是否有心肌梗死的发病率增加地铁司机。方法采用1976 ~ 1996年斯德哥尔摩县40 ~ 69岁男性人群病例对照研究数据。该研究纳入了医院出院和死亡登记中所有心肌梗死的首次事件。对照组是从一般人群中随机选择的。全国人口普查被用来提供关于职业的资料。共纳入22 311例病例和131496例对照。其中,54例患者和250例对照组曾担任地铁司机。结果地铁司机心肌梗死的相对危险度未增加。当地铁司机与其他体力劳动者相比为0.92[95%可信区间(95% CI) 0.68-1.25],当地铁司机与所有其他有收入的男性相比为1.06 (95% CI 0.78-1.43)。亚组分析显示,工作时间、潜伏时间或停止工作后的时间对心肌梗死的风险没有影响。结论斯德哥尔摩地铁司机心肌梗死发生率并不高于其他从业人员。
Objectives Particulate matter in urban air is associated with the risk of myocardial infarction in the general population. Very high levels of airborne particles have been detected in the subway system of Stockholm, as well as in several other large cities. This situation has caused concern for negative health effects among subway staff. The aim of this study was to investigate whether there is an increased incidence of myocardial infarction among subway drivers.Methods Data from a population-based case-control study of men aged 40-69 in Stockholm County in 19761996 were used. The study included all first events of myocardial infarction in registers of hospital discharges and deaths. The controls were selected randomly from the general population. National censuses were used for information on occupation. Altogether, 22 311 cases and 131496 controls were included. Among these, 54 cases and 250 controls had worked as subway drivers.Results The relative risk of myocardial infarction among subway drivers was not increased. It was 0.92 [95% confidence interval (95% CI) 0.68-1.25] when the subway drivers were compared with other manual workers and 1.06 (95% CI 0.78-1.43) when the subway drivers were compared with all other gainfully employed men. Subgroup analyses indicated no influence on the risk of myocardial infarction from the duration of employment, latency time, or time since employment stopped.Conclusions Subway drivers in Stockholm do not have a higher incidence of myocardial infarction than other employed persons.