How neurons die in Alzheimer's disease: Implications for neuroinflammation.
How neurons die in Alzheimer's disease: Implications for neuroinflammation.
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DOI：
10.1016/j.conb.2022.102575
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发表时间：
2022-08
影响因子：
5.7
通讯作者：
中科院分区：
文献类型：
--
作者：
Despite the long-standing observation of vast neuronal loss in Alzheimer’s disease (AD) our understanding of how and when neurons are eliminated is incomplete. While previous investigation has focused on apoptosis, several novel forms of cell death (i.e. necroptosis, parthanatos, ferroptosis, cuproptosis) have emerged that require further investigation. This review aims to collect evidence for different modes of neuronal cell death in AD and to also discuss how these different forms of cell death may impact the neuroinflammatory environment that prevails in the AD brain. Improved understanding of how neurons die may help to delineate disease pathogenesis, provide insights toward treatment, and aid in the development of improved animal models of AD.
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影响因子：
64.5
作者：
Dixon SJ;Lemberg KM;Lamprecht MR;Skouta R;Zaitsev EM;Gleason CE;Patel DN;Bauer AJ;Cantley AM;Yang WS;Morrison B 3rd;Stockwell BR
通讯作者：
Stockwell BR
影响因子：
64.8
作者：
通讯作者：
--
DOI：
10.2741/3297
发表时间：
2009-01-01
期刊：
Frontiers in bioscience (Landmark edition)
影响因子：
--
作者：
David KK;Andrabi SA;Dawson TM;Dawson VL
通讯作者：
Dawson VL
影响因子：
25
作者：
Caccamo, Antonella;Branca, Caterina;Oddo, Salvatore
通讯作者：
Oddo, Salvatore
影响因子：
6.3
作者：
Adamczak, Stephanie E.;Vaccari, Juan Pablo de Rivero;Keane, Robert W.
通讯作者：
Keane, Robert W.