AMYLOID FIBRILS FORMED FROM A SEGMENT OF THE PANCREATIC-ISLET AMYLOID PROTEIN
AMYLOID FIBRILS FORMED FROM A SEGMENT OF THE PANCREATIC-ISLET AMYLOID PROTEIN
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DOI：
10.1016/s0006-291x(88)80538-2
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发表时间：
1988-09-15
影响因子：
3.1
通讯作者：
WILEY, CA
中科院分区：
文献类型：
--
作者：
GLENNER, GG;EANES, ED;WILEY, CA
由胰岛淀粉样蛋白的20-29个残基形成的合成肽证实了一种扭曲的β-褶皱片状蛋白，这表明它是2型糖尿病朗格汉斯胰岛淀粉样原纤维形成的潜在贡献者。
A synthetic peptide formed from residues 20-29 of the pancreatic islet amyloid protein has the confirmation of a twisted .beta.-pleated sheet protein suggesting it is a potential contributor toward amyloid fibril formation in the islets of Langerhans in Type 2 diabetes mellitus.