Vascular risk factors in the Swiss population
Vascular risk factors in the Swiss population
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DOI：
10.1007/s00415-005-0838-4
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发表时间：
2005-10-01
影响因子：
6
通讯作者：
Mattle, HP
中科院分区：
文献类型：
--
作者：
Nedeltchev, K;Arnold, M;Mattle, HP
背景：识别卒中高危人群仍然是评估心血管发病率和死亡率负担的最佳方法。方法：对4458名瑞士人(男1741人，女2717人，平均年龄57.8±15岁)进行高血压(HT)、高胆固醇血症(HCH)、糖尿病(DM)、超重(OW)、肥胖(OB)、吸烟(SM)及其合并症的调查。结果：最常见的危险因素是氧气肿(50%)，其次是高血压(47%)、六氯环己烷(33%)、SM(13%)和DM(1.6%)。无危险因素者占19.9%，其中1例为41.5%，2例为33.8%，3例为4%，4例为0.9%。OW在男性中的患病率高于女性(53%对41%，P=0.02)。41-50岁和51-60岁的男性高于女性(49%比36%，P=0.01；52%比42%，P=0.02)。六氯环己烷和糖尿病的患病率在性别上没有差异。羟色胺、OW和六氯环己烷不仅是最常见的单项危险因素，而且最有可能相互聚集。结论：大多数瑞士人有一两个血管危险因素。到目前为止，OW和HT是最常见的，而且很可能相互聚集。对这两个因素进行小幅修改将显著降低中风和心肌梗死的发生率。
Background:Identification of the population at risk of stroke remains the best approach to assess the burden of cardiovascular morbidity and mortality. Methods:The prevalence of hypertension (HT), hypercholesterolemia (HCh), diabetes mellitus (DM), overweight (OW), obesity (OB), tobacco use (SM), and their combinations was examined in 4458 Swiss persons (1741 men and 2717 women, mean age 57.8 +/- 15 years), who volunteered for the present survey. Results:OW was the most prevalent risk factor (50%), followed by HT (47%), HCh (33%), SM (13%) and DM (1.6%). The proportion of persons without risk factors (RF) was 19.9%, with 1 RF 41.5%, 2 RF 33.8%, 3 RF 4%, and 4 RF 0.9%. OW was more prevalent in men than in women (53% vs. 41%, P=0.02). More men than women aged 41-50 years and 51-60 years had HT (49% vs. 36%, P=0.01, and 52% vs. 42%, P=0.02). The prevalence of HCh and DM did not show any sex-related differences. HT, OW and HCh were not only the most common single risk factors, but were also most likely to aggregate with each other. Conclusions:The majority of Swiss people have one or two vascular risk factors. OW and HT are by far most common and are likely to aggregate with each other. A small modification of these two factors would reduce the incidence of stroke and myocardial infarction significantly.