Synthetic, mechanistic and kinetic studies on the organo-nanocatalyzed synthesis of oxygen and nitrogen containing spiro compounds under ultrasonic conditions
Synthetic, mechanistic and kinetic studies on the organo-nanocatalyzed synthesis of oxygen and nitrogen containing spiro compounds under ultrasonic conditions
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DOI：
10.1039/c6gc00724d
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发表时间：
2016-07
期刊：
影响因子：
9.8
通讯作者：
N. Singh;Makroni Lily;S. P. Devi;Noimur Rahman;Aziz Ahmed;A. K. Chandra;R. Nongkhlaw
中科院分区：
文献类型：
--
作者：
N. Singh;Makroni Lily;S. P. Devi;Noimur Rahman;Aziz Ahmed;A. K. Chandra;R. Nongkhlaw
采用盐酸硫胺素包覆磁性Fe2O3@SiO2纳米粒子制备了一类新型的有机纳米催化剂。研究了其在超声催化合成含氧、含氮螺杂环化合物中的应用。该合成方法具有高效、经济、绿色的特点。用TEM、SEM、EDS、粉末XRD、VSM、FT-IR、TGA、DTA等手段对催化剂进行了表征。采用DFT：B3 LYP计算方法对盐酸硫胺的催化作用进行了机理和动力学研究。
A novel class of organo-nanocatalysts was fabricated by encapsulating magnetic Fe2O3@SiO2 nanoparticles with thiamine hydrochloride. Its catalytic application in the synthesis of oxygen and nitrogen containing spiro heterocycles via ultrasonication was thoroughly investigated. The synthetic protocol was found to be efficient, economical and green. The prepared catalyst was characterised by TEM, SEM, EDS, powder XRD, VSM, FT-IR, TGA, DTA, etc. Mechanistic and kinetic studies for the organic transformations were also carried out to determine the catalytic role of thiamine hydrochloride using a computational method viz. DFT: B3LYP.