CHARACTERIZATION OF SERUM FERRITIN IN IRON OVERLOAD - POSSIBLE IDENTITY TO NATURAL APOFERRITIN

CHARACTERIZATION OF SERUM FERRITIN IN IRON OVERLOAD - POSSIBLE IDENTITY TO NATURAL APOFERRITIN
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DOI:
10.1111/j.1365-2141.1977.tb00640.x
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发表时间:
1977-01-01
影响因子:
6.5
通讯作者:
DRYSDALE, JW
DRYSDALE, JW
中科院分区:
医学2区
文献类型:
--
作者:
AROSIO, P;YOKOTA, M;DRYSDALE, JW

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对1例血色素沉着症患者和1例输血铁质沉着症患者的血清铁蛋白与组织异铁蛋白的铁含量、异铁蛋白光谱和免疫学性质进行了比较。这两种血清铁蛋白的铁含量都很低,只对应于肝脏中最基本的异铁蛋白。血清铁蛋白与来自肝脏的天然载脂蛋白在各方面都非常相似。
Serum ferritins from a patient with hemochromatosis and from a patient with transfusional siderosis were compared with tissue isoferritins on the basis of their Fe content, isoferritin spectrum and immunological properties. Both serum ferritins had a low Fe content and corresponded to only the most basic isoferritins in liver. The serum ferritins were very similar to the natural apoferritin from liver in all respects.