Community-based malaria control in Saradidi, Kenya: description of the programme and impact on parasitaemia rates and antimalarial antibodies.
Community-based malaria control in Saradidi, Kenya: description of the programme and impact on parasitaemia rates and antimalarial antibodies.
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肯尼亚萨拉迪迪的社区疟疾控制：该计划的描述以及对寄生虫血症率和抗疟抗体的影响。
DOI：
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发表时间：
1987
影响因子：
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通讯作者：
D. Koech
中科院分区：
文献类型：
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作者：
H. C. Spencer;D. Kaseje;W. Collins;M. Shehata;A. Turner;P. S. Stanfill;A. Huong;J. Roberts;Michele Villinski;D. Koech
描述了 1982 年在肯尼亚萨拉迪迪启动的基于社区的疟疾控制计划。每个村庄都提供了由志愿社区卫生工作者提供的抗疟治疗。疟疾是全流行病。按年龄划分的寄生虫血症发生率很高，并且在控制计划开始后没有变化。恶性疟原虫是最常见的种类，在 8105 例感染中 98.2% 单独或混合存在。通过间接荧光抗体（IFA）测试，1981 年 5 月收集的 2040 个血液样本中几乎全部（98.5%）恶性疟原虫呈阳性（滴度倒数大于或等于 80）。所有年龄组的 IFA 测试或酶联免疫吸附测定 (ELISA) 中恶性疟原虫血清阳性率均较高，并且在纵向调查或定期跟踪的 0 至 9 岁儿童队列中没有显着变化。虽然疟疾控制计划成功地为每个村庄提供了治疗，但疟疾流行率并没有降低。仅寄生虫学和血清学研究不足以描述萨拉迪迪社区疟疾控制计划的影响。在寄生虫血症发生率没有任何下降的情况下，疟疾引起的发病率和死亡率可以下降，从而显着改善人口的健康。
A community-based malaria control programme initiated in Saradidi, Kenya in 1982 is described. Antimalarial treatment provided by volunteer community health workers was made available in each village. Malaria was holoendemic. Parasitaemia rates by age were high and did not change after the control programme began. Plasmodium falciparum was the most common species and was present alone or mixed in 98.2% of 8105 infections. Virtually all (98.5%) of 2040 blood samples collected in May 1981 were positive (reciprocal titre greater than or equal to 80) to P. falciparum by the indirect fluorescent antibody (IFA) test. Seropositivity rates to P. falciparum in the IFA test or the enzyme-linked immunosorbent assay (ELISA) were high in all age groups and did not change significantly in longitudinal surveys or in a cohort of children zero to nine years old followed at intervals. While the malaria control programme was successful in bringing treatment to each village, malaria prevalence was not reduced. Parasitologic and serologic studies alone were not adequate to describe the impact of the community-based malaria control programme in Saradidi. Morbidity and mortality rates caused by malaria can decline, significantly improving the health of the population, in the absence of any decrease in parasitaemia rates.