FOUR-DIMENSIONAL MEASUREMENT OF THE DISPLACEMENT OF INTERNAL FIDUCIAL MARKERS DURING 320-MULTISLICE COMPUTED TOMOGRAPHY SCANNING OF THORACIC ESOPHAGEAL CANCER
FOUR-DIMENSIONAL MEASUREMENT OF THE DISPLACEMENT OF INTERNAL FIDUCIAL MARKERS DURING 320-MULTISLICE COMPUTED TOMOGRAPHY SCANNING OF THORACIC ESOPHAGEAL CANCER
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DOI：
10.1016/j.ijrobp.2010.03.045
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发表时间：
2011-02-01
影响因子：
7
通讯作者：
Nakagawa, Keiichi
中科院分区：
文献类型：
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作者：
Yamashita, Hideomi;Kida, Satoshi;Nakagawa, Keiichi
目的：使用 320 多层 CT 研究放置在食管癌附近的内部基准标记的三维运动。方法和材料：本研究检查了 12 名接受外束光子放射治疗的患者原发肿瘤附近食管壁中的 22 个金属标记。在放疗位置的 20 秒电影 CT 期间，对 41 个呼吸阶段的运动评估进行了分析。结果：头尾 (CC) 方向的运动与大多数标记 (73%) 的呼吸曲线显示出很强的相关性 (R-2 > 0.4)。标记移动的平均绝对幅度在左右（LR）、前后（AP）和CC方向上分别为1.5+/-1.6mm、1.6+/-1.7mm和3.3+/-3.3mm。对于上、中、下胸段食管，22 个夹子在呼气峰值和吸气峰值之间 CC 方向的平均标记位移分别为 1.1 mm（最大 5.5 mm）、3.0 mm（14.5 mm）和 5.1 mm（16.3 mm）。结论：用 320 多层 CT 评估原发性食管肿瘤的运动。根据这项研究，上段食管的 4.3 mm CC、1.5 mm AP 和 2.0 mm LR，中部的 7.4 mm CC、3.0 mm AP 和 2.4 mm LR，以及下胸段食管的 13.8 mm CC、6.6 mm AP 和 6.8 mm LR 覆盖了我们研究人群中 95% 的病例的肿瘤运动。 (C) 2011 爱思唯尔公司
Purpose: To investigate the three-dimensional movement of internal fiducial markers placed near esophageal cancers using 320-multislice CT.Methods and Materials: This study examined 22 metal markers in the esophageal wall near the primary tumors of 12 patients treated with external-beam photon radiotherapy. Motion assessment was analyzed in 41 respiratory phases during 20 s of cine CT in the radiotherapy position.Results: Motion in the cranial caudal (CC) direction showed a strong correlation (R-2 > 0.4) with the respiratory curve in most markers (73%). The average absolute amplitude of the marker movement was 1.5 +/- 1.6 mm, 1.6 +/- 1.7 mm, and 3.3 +/- 3.3 mm in the left right (LR), anterior posterior (AP), and CC directions, respectively. The average marker displacements in the CC direction between peak exhalation and inhalation for the 22 clips were 1.1 mm (maximum, 5.5 mm), 3.0 mm (14.5 mm), and 5.1 mm (16.3 mm) for the upper, middle, and lower thoracic esophagus, respectively.Conclusions: Motion in primary esophagus tumor was evaluated with 320-multislice CT. According to this study, 4.3 mm CC, 1.5 mm AP, and 2.0 mm LR in the upper, 7.4 mm CC, 3.0 mm AP, and 2.4 mm LR in the middle, and 13.8 mm CC, 6.6 mm AP, and 6.8 mm LR in the lower thoracic esophagus provided coverage of tumor motion in 95% of the cases in our study population. (C) 2011 Elsevier Inc.