Relationship between Sleep Disturbance and Functional Outcomes in Daily Life Habits of Children with Down Syndrome
Relationship between Sleep Disturbance and Functional Outcomes in Daily Life Habits of Children with Down Syndrome
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DOI：
10.5665/sleep.4326
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发表时间：
2015-01-01
期刊：
影响因子：
5.6
通讯作者：
Herting, Jerald R.
中科院分区：
文献类型：
--
作者：
Churchill, Shervin S.;Kieckhefer, Gail M.;Herting, Jerald R.
目的：描述唐氏综合征(DS)儿童的睡眠模式和日常生活习惯的完成情况，探讨睡眠障碍主观指标与日常生活功能结果的关系。设计：横断面研究，以互联网为样本。背景：在家中填写在线调查问卷。参与者：110名唐氏综合征儿童的父母和29名发育典型儿童(TD)的父母，年龄5~18岁。干预：N/A。测量和结果：采用儿童睡眠习惯问卷收集8个领域(子量表)的睡眠障碍信息和总分。生活习惯问卷(Life-H)收集了11个领域的日常生活习惯信息。多变量回归模型被用来评估睡眠障碍和日常生活习惯的完成之间的关联。睡眠呼吸障碍(SDB)对11种日常生活习惯中的10种和生活质量总分有显著的解释作用。与一般发育儿童相比，睡眠焦虑和睡眠障碍对DS儿童生活习惯的形成有显着影响。当与睡眠障碍的其他7个领域一起进行多变量模型评估时，SDB是生活习惯完成的最主要解释因素。结论：睡眠障碍与日常生活功能的完成呈负相关。预防和治疗唐氏综合症儿童的睡眠问题，特别是睡眠呼吸障碍，可能会促进日常生活习惯和活动的完成。
Objectives: The goal of this study was to describe sleep patterns and accomplishment of daily life habits in children with Down syndrome (DS) and to investigate the relationship between subjective indicators of sleep disturbance with functional outcomes in daily life.Design: Cross-sectional study with an Internet sampleSetting: Online survey filled out at homeParticipants: 110 parents of children with DS and 29 parents of children with typical development (TD), age 5 to 18 years.Interventions: N/A.Measurements and Results: Children's Sleep Habits Questionnaire was employed to collect information about sleep disturbances in 8 domains (subscales) and a total score. The Life Habits questionnaire (Life-H) sampled information about daily life habits in 11 domains. Multivariable regression modeling was used to assess the associations between sleep disturbances and the accomplishment of daily life habits. Sleep disordered breathing (SDB) was a significant explanatory factor in 10 of 11 daily life habits and the total Life-H score. Sleep anxiety and parasomnias significantly influenced the accomplishment of life habits in children with DS as compared to children with typical development. When evaluated in multivariable models in conjunction with the other 7 domains of sleep disturbances, SDB was the most dominant explanatory factor for accomplishment of life habits.Conclusions: Sleep disturbances are negatively related to accomplishment of daily life functions. Prevention and treatment of sleep problems, particularly sleep disordered breathing, in children with Down syndrome may lead to enhanced accomplishment of daily life habits and activities.