Combatting mucosal melanoma: recent advances and future perspectives.
Combatting mucosal melanoma: recent advances and future perspectives.
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DOI：
10.2217/mmt-2018-0003
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发表时间：
2018-09
影响因子：
3.6
通讯作者：
Payne M
中科院分区：
文献类型：
--
作者：
Tyrrell H;Payne M
粘液性黑色素瘤是黑色素瘤的一种罕见亚型，预后特别差。由于诊断的罕见性，以及近年来皮肤黑色素瘤管理的发展速度，几乎没有很好的证据来指导管理，英国仍在制定循证临床指南。在这篇综述中，我们提供了一个粘膜黑色素瘤的管理概述，突出皮肤和粘膜黑色素瘤之间的关键差异，检查这种疾病的全身治疗的最新进展和可能的未来方向。
Mucosal melanomas are a rare subtype of melanoma and are associated with a particularly poor prognosis. Due to the rarity of the diagnosis, and the pace with which the management of cutaneous melanoma has evolved over recent years, there is little good evidence to guide management and evidence-based clinical guidelines are still in development in the UK. In this review we provide an overview of the management of mucosal melanoma, highlighting the critical differences between cutaneous and mucosal melanomas, before examining recent advances in the systemic treatment of this disease and likely future directions.