Ventilatory response to exercise and to CO 2 rebreathing in normal subjects.
Ventilatory response to exercise and to CO 2 rebreathing in normal subjects.
复制标题
正常受试者对运动和 CO 2 再呼吸的通气反应。
DOI：
10.1042/cs0430861
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发表时间：
1972
期刊：
影响因子：
6
通讯作者：
E. Campbell
中科院分区：
文献类型：
--
作者：
A. Rebuck;Norman L. Jones;E. Campbell
1. 对 11 名正常受试者测量渐进运动期间通气的变化。使用再呼吸方法测量同一受试者在休息时对二氧化碳的通气反应。
2. 运动通气反应范围为 16·6–32·0 升·分钟−1 (升 CO2·分钟−1)−1（平均 22·7；标准差 5·35）；对 O2 吸收的反应为 17·0–43·9 升 min−1 (升 O2 min−1)−1（平均值 29·02；SD 9·07）。对 CO2 的通气反应 (S co2) 范围为 0·81 至 3·22 升 min−1 mmHg−1（平均值 1·87；SD 0·62）。
3. CO2 输出或O2 吸收增加的响应变化与S co2 之间存在高度显着的相关性（P < 0·001）。
4. 结果与正常受试者运动期间的通气量与其对 CO2 的化学敏感性直接相关的建议相一致，具有最高敏感性的人表现出最大的运动通气量。
1. Changes in ventilation during progressive exercise were measured in eleven normal subjects. Ventilatory response to carbon dioxide at rest was measured in the same subjects using a rebreathing method.
2. The range of ventilatory response to exercise was 16·6–32·0 litres min−1 (litres CO2 min−1)−1 (mean 22·7; SD 5·35); response to O2 uptake was 17·0–43·9 litres min−1 (litres O2 min−1)−1 (mean 29·02; SD 9·07). Ventilatory response to CO2 ( S co2) ranged from 0·81 to 3·22 litre min−1 mmHg−1 (mean 1·87; SD 0·62).
3. There was a highly significant ( P < 0·001) correlation between the changes in response to increasing CO2 output or O2 uptake, and S co2.
4. The results are compatible with the suggestion that ventilation during exercise in normal subjects is directly related to their chemosensitivity to CO2, those having the highest sensitivity showing the greatest exercise ventilation.