HETEROSEXUALLY TRANSMITTED HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION AMONG PREGNANT-WOMEN IN A RURAL FLORIDA COMMUNITY
HETEROSEXUALLY TRANSMITTED HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION AMONG PREGNANT-WOMEN IN A RURAL FLORIDA COMMUNITY
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DOI：
10.1056/nejm199212103272402
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发表时间：
1992-12-10
影响因子：
158.5
通讯作者：
WITTE, JJ
中科院分区：
文献类型：
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作者：
ELLERBROCK, TV;LIEB, S;WITTE, JJ
背景在美国，越来越多的感染人体免疫缺陷病毒（艾滋病毒）的妇女生活在非大都市地区。然而，人们对大城市以外的妇女传播艾滋病毒的危险因素知之甚少。我们采访并测试了1082（99.8%）的1084连续孕妇谁登记在公共卫生诊所在西部棕榈海滩县，佛罗里达产前护理。这个大约有36，000人的农村农业地区是已知的艾滋病毒感染的高流行率。艾滋病毒血清阳性率为5.1%（1 011名妇女中有52名）。非海地裔或西班牙裔的黑人女性感染率最高（8.3%[575人中有48人]）。1009名妇女中只有4人（0.4%）报告曾注射毒品，4人的艾滋病毒血清呈阴性;然而，43名“快克”可卡因使用者中有14人（33%）感染了艾滋病毒。在产前登记时，983名妇女中有131名（13%）淋病、衣原体感染或梅毒检测呈阳性。通过多变量逻辑回归分析，发现HIV感染与使用快克可卡因独立相关（比值比，3.3; P
Background. In the United States, an increasing proportion of women infected with the human immunodeficiency virus (HIV) live in nonmetropolitan areas. Little is known, however, about the risk factors for HIV transmission in women outside large cities.Methods. We interviewed and tested 1082 (99.8 percent) of 1084 consecutive pregnant women who registered for prenatal care at a public health clinic in western Palm Beach County, Florida. This rural agricultural area of about 36,000 people is known to have a high prevalence of HIV infection.Results. The seroprevalence of HIV was 5.1 percent (52 of 1011 women). Black women who were neither Haitian nor Hispanic had the highest rate of infection (8.3 percent [48 of 575]). Only 4 of 1009 women (0.4 percent) reported ever injecting drugs, and the 4 were HIV-sero-negative; however, 14 of 43 users of "crack" cocaine (33 percent) had HIV infection. At prenatal registration, 131 of 983 women (13 percent) tested positive for gonorrhea, chlamydial infection, or syphilis. By multivariate logistic-regression analysis, HIV infection was found to be independently associated with having used crack cocaine (odds ratio, 3.3; P