Anti-hyperglycemic and anti-oxidative activities of ginseng polysaccharides in STZ-induced diabetic mice
Anti-hyperglycemic and anti-oxidative activities of ginseng polysaccharides in STZ-induced diabetic mice
复制标题
人参多糖对 STZ 诱导的糖尿病小鼠的抗高血糖和抗氧化活性
DOI：
10.1039/c3fo60326a
复制
发表时间：
2014-05-01
期刊：
影响因子：
6.1
通讯作者：
Zhou, Yifa
中科院分区：
文献类型：
--
作者：
Sun, Chengxin;Chen, Yan;Zhou, Yifa
从人参多糖中分离得到中性多糖（WGPN）和酸性多糖（WGPA）。WGPN和WGPA通过不同的给药方式降低空腹血糖。胃内给药WGPA显示出明显的降血糖作用，这可能与其抗氧化活性有关。结果表明，WGPA可能具有抗糖尿病的潜力。
Neutral (WGPN) and acidic (WGPA) polysaccharides were fractionated from ginseng polysaccharide. WGPN and WGPA decreased fasting blood glucose by different manners of administration. Intra-gastric administration of WGPA showed a marked hypoglycemic effect, which may be related to its anti-oxidative activity. The results indicated that WGPA may have anti-diabetic potential.