Individual and neighborhood socioeconomic status characteristics and prevalence of metabolic syndrome: the Atherosclerosis Risk in Communities (ARIC) Study.

Individual and neighborhood socioeconomic status characteristics and prevalence of metabolic syndrome: the Atherosclerosis Risk in Communities (ARIC) Study.
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DOI:
10.1097/psy.0b013e318183a491
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发表时间:
2008-11
影响因子:
3.3
通讯作者:
Heiss G
Heiss G
中科院分区:
医学3区
文献类型:
--
作者:
Chichlowska KL;Rose KM;Diez-Roux AV;Golden SH;McNeill AM;Heiss G

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本研究的目的是在社区动脉粥样硬化风险(ARIC)研究(1987-99)中检查个人社会经济地位(iSES)和社区SES(nSES)与代谢综合征(MetS)患病率的关系。参与者包括2,932名黑人和9,777名白色男性和女性,年龄在45至64岁之间,基线时没有糖尿病。过去12个月的家庭总收入和六个人口普查区域的社会经济指标结合成一个综合指数,分别用于量化iSES和nSES。Poisson回归用于评估iSES和nSES对MetS的联合贡献的相关性,按性别和种族分层,并调整多个协变量。对于包括nSES的分析,使用了分层建模技术。使用2005年ATP III标准,在40%的黑人女性、30%的白色女性、28%的黑人男性和35%的白色男性中确定了MetS。在黑人和白色男性中,MetS与iSES或nSES之间没有关联。相比之下,在调整风险因素后,低(L)-iSES和中等(M)-iSES的黑人和白色女性比高iSES的女性更容易患MetS。L-nSES和M-nSES的模式相似但较弱。总之,iSES和nSES与女性MetS患病率增加独立相关,但与男性无关。旨在了解这些性别差异的原因的努力可能会提供深入了解减少代谢综合征及其慢性疾病后遗症的患病率的途径。
The objective of this study was to examine the association of individual socioeconomic status (iSES) and neighborhood SES (nSES) on the prevalence of metabolic syndrome (MetS) in the Atherosclerosis Risk in Communities (ARIC) Study, (1987–99). Participants included 2,932 black and 9,777 white men and women ages 45 to 64 years without diabetes at baseline. Total combined family income for the past 12 months and six census tract socioeconomic measures combined into a composite index were used to quantify iSES and nSES, respectively. Poisson regression was used to assess associations of the joint contribution of iSES and nSES on the MetS, stratified by gender and race and adjusting for multiple covariates. For analyses that included nSES, hierarchical modeling techniques were used. Using 2005 ATP III criteria, MetS was identified in 40% of black women, 30% of white women, 28% of black men and 35% of white men. Among black and white men, there was no association between MetS and iSES or nSES. In contrast, after adjustment for risk factors, black and white women with low (L)-iSES and medium (M)-iSES were more likely to have MetS than those with high-iSES. Similar but weaker patterns were noted for L-nSES and M-nSES. In summary, both iSES and nSES were independently associated with an increased prevalence of MetS among women but not men. Efforts aimed at understanding the causes of these gender differences may offer insight into avenues for reducing the prevalence of the MetS and its chronic disease sequelae.