Patterns of diabetic macular edema with optical coherence tomography
Patterns of diabetic macular edema with optical coherence tomography
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DOI：
10.1016/s0002-9394(99)00033-1
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发表时间：
1999-06-01
影响因子：
4.2
通讯作者：
Maruyama, Y
中科院分区：
文献类型：
--
作者：
Otani, T;Kishi, S;Maruyama, Y
目的：我们通过光学相干断层扫描报告糖尿病黄斑水肿的横截面图像以及断层扫描特征与最佳矫正视力之间的相关性。方法：在一项前瞻性研究中，对 42 名糖尿病黄斑水肿患者的 59 只眼睛和 10 名正常对照受试者的 10 只眼睛进行了光学相干断层扫描。结果：光学相干断层扫描显示糖尿病黄斑的三种结构变化模式水肿：海绵样视网膜肿胀（59 只眼中的 52 只 [88%]）、黄斑囊样水肿（59 只眼中的 28 只 [47%]）和浆液性视网膜脱离（59 只眼中的 9 只 [15%]）。有些眼睛有不止一种病理改变。视网膜肿胀在视网膜外层较内层更为明显，黄斑囊样水肿主要发生在视网膜外层，长期存在黄斑囊样水肿的眼睛，囊样间隙已融合，导致囊样腔变大，几乎累及整个视网膜层。硬性渗出物为高反射区，位于视网膜外层，无黄斑囊样水肿眼的中央凹视网膜厚度与最佳矫正视力呈中度负相关（相关系数：-0.61，P < .01）。结论：糖尿病性黄斑水肿涉及三种结构性改变，包括海绵状视网膜肿胀（88%）、黄斑囊样水肿。水肿（47%）和浆液性视网膜脱离（15%），无论断层扫描特征如何，最佳矫正视力与视网膜厚度中度相关。 （美国眼科杂志 1999 年；127：688-693。(C) 1999 年，Elsevier Science Inc. 保留所有权利。）。
PURPOSE: We report cross-sectional images of diabetic macular edema and correlation between tomographic features and visual acuity with best correction by means of optical coherence tomography,METHOD: In a prospective study, optical coherence tomography was performed in 59 eyes of 42 patients with diabetic macular edema and in 10 eyes of 10 normal control subjects.RESULTS: Optical coherence tomography showed three patterns of structural changes in diabetic macular edema: sponge like retinal swelling (52 [88%] of 59 eyes), cystoid macular edema (28 [47%] of 59 eyes), and serous retinal detachment (9 [15%] of 59 eyes). Some eyes had more than one pathologic change. Retinal swelling was more pronounced in the outer rather than the inner retinal layers, Cystoid macular edema was located mainly in the outer retinal layers, In eyes with long-standing cystoid macular edema, cystoid spaces had fused, resulting in a large cystoid cavity involving almost the entire retinal layer. Hard exudates were seen as highly reflective areas Located in the outer retinal layers, The retinal thickness at the central fovea and the visual acuity with best correction showed an intermediate negative correlation in eyes without cystoid macular edema (correlation coefficient: -0.61, P < .01).CONCLUSIONS: Diabetic macular edema involved three structural changes, including-sponge-like retinal swelling (88%), cystoid macular edema (47%), and serous retinal detachment (15%), Visual acuity with best correction moderately correlated with retinal thickness regardless of the different tomographic features. (Am J Ophthalmol 1999;127:688-693. (C) 1999 by Elsevier Science Inc. All rights reserved.).