Influenza A and B virus infections in children
Influenza A and B virus infections in children
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DOI：
10.1086/345909
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发表时间：
2003-02-01
影响因子：
11.8
通讯作者：
Ruuskanen, O
中科院分区：
文献类型：
--
作者：
Peltola, V;Ziegler, T;Ruuskanen, O
为了获得有关感染的临床表现、年龄分布和严重到需要医院转诊的儿童的基本情况的数据，我们对1980-1999年间在图尔库大学医院(芬兰图尔库)接受治疗的儿童进行了回顾性研究。在15,420名被研究的儿童中，有683人的鼻咽吸出物中检测到了甲型或乙型流感抗原。甲型流感儿童的中位年龄为2.0岁(n=544)，乙型流感儿童的中位年龄为4.2岁(n=139)(P<；.001)。四分之一的儿童有潜在的健康状况。高烧、咳嗽和鼻漏是最常见的症状。24%的儿童发展为急性中耳炎，9%的儿童发展为肺炎。研究表明，大多数因儿童流感而住院的患者涉及以前健康的婴儿和幼儿。流感的实验室确认对儿童特别重要，因为感染的临床表现没有成人那么典型。
To obtain data on the clinical manifestations of infection, the age distribution, and the underlying conditions of children with influenza severe enough to lead to hospital referral, we performed a retrospective study of children treated at Turku University Hospital (Turku, Finland) in 1980-1999. Influenza A or B antigen was detected in the nasopharyngeal aspirates of 683 of the 15,420 children studied. The median age of children with influenza A was 2.0 years (n = 544), and that of children with influenza B was 4.2 years (n=139) (P < .001). One-fourth of the children had an underlying medical condition. High fever, cough, and rhinorrhea were the most frequently recorded symptoms. Acute otitis media developed in 24% of the children, and pneumonia developed in 9% of the children. The study shows that the majority of patient hospitalizations for pediatric influenza involve previously healthy infants and young children. Laboratory confirmation of influenza is particularly important for children because the clinical presentation of the infection is less characteristic than that seen in adults.