OVERALL AND CORONARY HEART-DISEASE MORTALITY-RATES IN RELATION TO MAJOR RISK-FACTORS IN 325,348 MEN SCREENED FOR THE MRFIT
OVERALL AND CORONARY HEART-DISEASE MORTALITY-RATES IN RELATION TO MAJOR RISK-FACTORS IN 325,348 MEN SCREENED FOR THE MRFIT
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DOI：
10.1016/0002-8703(86)90481-3
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发表时间：
1986-10-01
影响因子：
4.8
通讯作者：
KJELSBERG, MO
中科院分区：
文献类型：
--
作者：
KANNEL, WB;NEATON, JD;KJELSBERG, MO
最初对325,384名白人中年男性进行多风险因素干预试验(MRFIT)的筛查，可以详细检查风险因素与冠心病(CHD)死亡率的关系。可以获得比以前更准确的风险估计，特别是在风险因素分布的低端。可以更好地了解风险因素对死亡率的影响的年龄趋势，并可以研究风险因素之间的其他相互作用。风险因素的净效应和联合效应可以直接从样本数据以及多变量统计估计中确定。这些都是本报告的目标。
The original screening of 325,384 white middle-aged men for the Multiple Risk Factor Intervention Trial (MRFIT) allows detailed examination of the relationship of risk factors to coronary heart disease (CHD) mortality rates. More precise estimates of risk than were previously available can be obtained, particularly at the low end of the risk factor distribution. Better insight into age trends in risk factor impact on mortality rates may be obtained and other interactions between the risk factors can be studied. The net and joint effects of the risk factors can be determined directly from the sample data as well as from multivariate statistical estimates. These are the objectives of this report.