Mathematical modelling of magnetically targeted drug delivery
Mathematical modelling of magnetically targeted drug delivery
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DOI：
10.1016/j.jmmm.2005.02.040
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发表时间：
2005-05-01
影响因子：
2.7
通讯作者：
Richardson, G
中科院分区：
文献类型：
--
作者：
Grief, AD;Richardson, G
建立了磁性颗粒靶向给药的数学模型。这包括由微循环中红细胞之间的相互作用引起的颗粒弥漫性通量。该模型用于跟踪船舶网络中的粒子。讨论了磁场设计，我们表明，不可能使用外部施加的磁场来特定地瞄准内部区域。(c) 2005 Elsevier B.V.版权所有
A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the microcirculation. The model is used to track particles in a vessel network. Magnetic field design is discussed and we show that it is impossible to specifically target internal regions using an externally applied field. (c) 2005 Elsevier B.V. All rights reserved.