Giant vesicles undergoing alkylation reactions observed by optical microscopy
Giant vesicles undergoing alkylation reactions observed by optical microscopy
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光学显微镜观察到正在进行烷基化反应的巨型囊泡
DOI：
10.1021/la011803i
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发表时间：
2002
期刊：
影响因子：
3.9
通讯作者：
Theotis Clark
中科院分区：
文献类型：
--
作者：
D. Jaeger;Theotis Clark
通过相差光学显微镜观察到功能化的双链表面活性剂1（2-肼基-N-甲基-N，N-双十二烷基-2-氧代乙铵溴化物）的巨囊泡（GV），因为它们在23 °C下在pH 9.0的硼酸盐缓冲液中与2（O-甲基S-苄基苯基硫代膦酸酯）发生化学反应。GV被损坏，并最终转化为油状液滴。此外，通过同时光学和落射荧光显微镜观察含有荧光染料7（碘化1-甲基-7-羟基喹啉）的1的GV，因为它们与2进行反应。这些反应导致GVs中7的损失。
Giant vesicles (GVs) of functionalized, double-chain surfactant 1 (2-hydrazino-N-methyl-N,N-didodecyl-2-oxoethanaminium bromide) were observed by phase-contrast optical microscopy as they underwent chemical reactions with 2 (O-methyl S-benzyl phenylphosphonothioate) in a pH 9.0 borate buffer at 23 °C. The GVs were damaged and ultimately converted into oil-like droplets. Also, GVs of 1 containing fluorescent dye 7 (1-methyl-7-hydroxyquinolinium iodide) were observed by simultaneous optical and epifluorescence microscopy as they underwent reactions with 2. The reactions effected the loss of 7 from the GVs.