Silica coating improves the efficacy of Pd nanosheets for photothermal therapy of cancer cells using near infrared laser.
Silica coating improves the efficacy of Pd nanosheets for photothermal therapy of cancer cells using near infrared laser.
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DOI：
10.1039/c1cc10451a
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发表时间：
2011-03
影响因子：
4.9
通讯作者：
Shaoheng Tang;Xiaoqing Huang;N. Zheng
中科院分区：
文献类型：
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作者：
Shaoheng Tang;Xiaoqing Huang;N. Zheng
厚度很重要！1.8纳米厚的钯纳米片超薄的特性使其无法有效地进入细胞。通过二氧化硅涂层以及表面功能化，现已使细胞对钯纳米片的摄取提高了13倍，从而显著提高了它们的近红外光热细胞杀伤效力。
Thickness does matter! The ultrathin nature of 1.8 nm-thick Pd nanosheets prevents them entering cells effectively. A 13-times enhancement in the cells' uptake of the Pd nanosheets has now been achieved by silica coating together with surface functionalization, therefore significantly improving their NIR photothermal cell-killing efficacy.