SERUM HUMAN CHORIONIC-GONADOTROPIN LEVELS THROUGHOUT NORMAL-PREGNANCY
SERUM HUMAN CHORIONIC-GONADOTROPIN LEVELS THROUGHOUT NORMAL-PREGNANCY
复制标题
DOI：
10.1016/0002-9378(76)90518-4
复制
发表时间：
1976-01-01
影响因子：
9.8
通讯作者：
WADE, ME
中科院分区：
文献类型：
--
作者：
BRAUNSTEIN, GD;RASOR, J;WADE, ME
通过β-hCG测定443名孕妇血清中的人绒毛膜促性腺激素（hCG）水平。hCG放射免疫测定法，以确定通过特异性较低的免疫测定法观察到的hCG水平的第3个三月次峰是否是由于交叉反应物质所致。hCG最早在推定受孕后6天检测到，并在56 - 68天之间达到高峰，在18周时达到最低点。hCG水平没有继发性升高，表明非特异性hCG免疫测定在妊娠最后三个月给出了虚假的高hCG值。
Human chorionic gonadotropin (hCG) levels were measured in the sera of 443 pregnant women by the .beta.-hCG radioimmunoassay in order to determine if the 3rd-trimester secondary peak in hCG levels observed by less specific immunoassays was due to cross-reacting substances. hCG was detected as early as 6 days after presumed conception and peaked between 56 and 68 days, with a nadir at 18 wk. No secondary rise in hCG levels was demonstrated, indicating that the nonspecific hCG immunoassays give spuriously high values for hCG during the last trimester of pregnancy.