Highly relaxing gadolinium based MRI contrast agents responsive to Mg2+ sensing
Highly relaxing gadolinium based MRI contrast agents responsive to Mg2+ sensing
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DOI：
10.1039/c2cc30757j
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发表时间：
2012-01-01
影响因子：
4.9
通讯作者：
Charbonniere, Loic J.
中科院分区：
文献类型：
--
作者：
Abada, Sabah;Lecointre, Alexandre;Charbonniere, Loic J.
A Gd complex based on a polyphosphonated pyridyl ligand shows a very high stability in aqueous solution (log K-EuL = 25.7), a high relaxivity (8.5 mM(-1) s(-1) at 25 degrees C and 20 MHz) and a marked and selective relaxivity enhancement (37%) in the presence of Mg2+, opening interesting perspectives for the design of cation responsive contrast agents.
