Sodium MRI of human articular cartilage in vivo
Sodium MRI of human articular cartilage in vivo
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DOI：
10.1002/mrm.1910390505
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发表时间：
1998-05-01
影响因子：
3.3
通讯作者：
Leigh, JS
中科院分区：
文献类型：
--
作者：
Reddy, R;Insko, EK;Leigh, JS
提出了人髌骨关节软骨体内钠 MRI 的初步结果。体外牛髌骨生成的钠图像清楚地区分了蛋白聚糖耗尽的区域和健康软骨的区域。这提供了第一个证据，表明钠成像可用于检测体内骨关节炎引起的变化，讨论了优化成像时间酸信噪比的过程，以及检测骨关节炎变化的潜在影响。
Preliminary results from in vivo sodium MRI of human patellar articular cartilage are presented. Sodium images generated of an in vitro bovine patella clearly distinguish the region of proteoglycan depletion from the region of healthy cartilage. This provides the first evidence that sodium imaging may be used to detect changes due to osteoarthritis in vivo, The process of optimizing imaging time acid signal-to-noise ratio, as well as potential implications in the detection of osteoarthritic change, are discussed.